Results 41 to 50 of about 376,320 (257)

Comparing Intra-Articular Corticosteroids and Platelet-rich Plasma for Knee Osteoarthritis Pain: A Prospective Quasi-comparative Study

Indian Journal of Pain
Background and Aim: Intra-articular (I/A) corticosteroids (CS) are used for short to mid-term pain relief in knee osteoarthritis (KOA). Newer therapies such as platelet-rich plasma (PRP) are believed to induce regenerative changes and decrease pain. Ours
Khuboo Rana, Suruchi Ambasta, Shivani Rastogi, Suraj Kumar, Shamrendra Narayan, Anurag Agarwal   +5 more
doaj   +1 more source

An Early Intensive Intervention for Inducing Inactive Asthma in Adults —A One-Year Follow-Up Observation Study—

Allergology International, 2011
Background: Treatment strategy that reduces dependence on long-term medication for chronic asthma is preferable. The purpose of the study is to investigate the efficacy of an early intensive intervention for inducing inactive asthma in adults and ...
Koichiro Kudo, Hiroko Arioka, Yuichiro Takeda, Takuro Shimbo, Satoko Handa, Akihiko Kawana, Mitsuhiro Kamimura, Yasuhiro Yamauchi, Hiroyuki Nagase, Nobuyuki Kobayashi, Toshie Manabe, Junzaburo Kabe   +11 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Successful management of chronic eosinophilic pneumonia triggered by immune checkpoint inhibitor: a case report and literature review

Frontiers in Immunology
Immune checkpoint inhibitors (ICIs) enhance antitumor immunity by blocking inhibitory immune signals, but can lead to immune-related adverse events (irAEs). Therefore, effective management of irAEs is crucial during ICI therapy.
Yasuhito Suzuki, Junpei Saito, Satoshi Kubota, Masakazu Ikeda, Mami Rikimaru, Ryuki Yamada, Takahiro Kumanaka, Ryutaro Tanaka, Kentaro Kazama, Koshi Saito, Rina Harigane, Riko Sato, Hikaru Tomita, Natsumi Watanabe, Takashi Umeda, Ryuichi Togawa, Yuki Sato, Takefumi Nikaido, Xintao Wang, Kenya Kanazawa, Yoshinori Tanino, Shigeyuki Murono, Yoko Shibata   +22 more
doaj   +1 more source

Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial

Journal of Pharmacopuncture, 2020
Objectives: Atopic dermatitis (AD) is a prevalent and chronic, pruritic inflammatory skin condition that can influence all age groups. AD is associated with a poor health-related quality of life.
Yunes Panahi, Nassim Rastgar, Ali Zamani, Amirhossein Sahebkar   +3 more
doaj   +1 more source

Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain [PDF]

, 2012
Total glucocorticoid hormone levels in plasma of various species, including humans, follow a circadian rhythm that is made up from an underlying series of hormone pulses. In blood most of the glucocorticoid is bound to corticosteroid-binding globulin and
Linthorst, Astrid C E, Droste, Susanne K, Reul, Johannes M H M, Qian, Xiaoxiao, Lightman, Stafford L   +4 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

A Systematic Review of Treatment for Acute Interstitial Nephritis

Kidney International Reports
Introduction: Acute interstitial nephritis (AIN) is a common cause of acute kidney injury. It is characterized by tubular inflammation with eosinophils histologically.
Yalin Yu, Erik Biros, Xiao Chang, Andrew J. Mallett   +3 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver

Molecular Therapy: Methods & Clinical Development
The multi-administration of recombinant adeno-associated virus (rAAV) is limited largely by immunological barriers. Herein, a novel strategy, named rAAV pseudo-lipid nanoparticle combined with triamcinolone acetonide (LNP-rAAV + TAC), has been described ...
Chunmei Gan, Mi Leng, Yu Liu, Zhaoyue Zheng, Siwu He, Wen Qiao, Lin Xiao, Yao Xiao, Jingya Ye, Lixing Zhou, Jiao Zhou, Boduan Xiao, Wenxin Zhao, Jiamei Yang, Aohan Wu, Huiyuan Zhang, Hongbo Hu, Xiaobo Cen, Zhiyong Qian, Haohao Dong, C. Alexander Valencia, Lunzhi Dai, Hoi Yee Chow, Lei Zhang, Biao Dong   +24 more
doaj   +1 more source