Results 71 to 80 of about 340,216 (249)

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

The Efficacy of Oral/Intravenous Corticosteroid Use in COVID-19 Patients: A Systematic Review

Journal of Experimental Pharmacology
Irma Rahayu Latarissa,1,2 Farida Rendrayani,1 Ghina Nadhifah Iftinan,2 Cecep Suhandi,3 Anna Meiliana,1,4 Ida Paulina Sormin,5,6 Melisa Intan Barliana,7,8 Keri Lestari1,2,8 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy ...
Latarissa IR, Rendrayani F, Iftinan GN, Suhandi C, Meiliana A, Sormin IP, Barliana MI, Lestari K   +7 more
doaj  

Betamethasone latency period and neonatal hypoglycemia in term infants

The Journal of Maternal-Fetal & Neonatal Medicine
Introduction Infants exposed to antenatal betamethasone (BMZ) between 34.0 and 36.6 weeks gestational age (GA) have increased risk for neonatal hypoglycemia, a known cause of brain injury.
Lauren A. Buckley, Briana Clifton, Katelyn M. Tessier, Connor Demorest, Raghavendra B. Rao, Sarah A. Wernimont   +5 more
doaj   +1 more source

Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants

Advanced Healthcare Materials, EarlyView.
A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta, Nikolaos Salaris, Ashish Kalkal, Fernando Yuen Chang, Maryam Javed, Azhar Ali Khan, Priya Mandal, Stavroula Balabani, Reza Motallebzadeh, Manish K. Tiwari   +9 more
wiley   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

0.2% Betamethasone Sodium Phosphate: A Multicenter, Randomized, Double-Masked Study to Compare Its Ocular Safety, Tolerability, and Efficacy to Vehicle in Cataract Surgery Subjects

Clinical Ophthalmology, 2023
Kamran Hosseini,1 Subba Gollamudi,2 Harvey Reiser,3 Tom Walters,4 Richard L Lindstrom5 1Surface Ophthalmics, Pleasanton, CA, USA; 2VRF Eye Specialty Group, Memphis, TN, USA; 3Eye Care Specialists, Kingston, PA, USA; 4Texan Eye, PA — Keystone Research ...
Hosseini K, Gollamudi S, Reiser H, Walters T, Lindstrom RL   +4 more
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Possibilities of Inner Ear Barrier Models for Otologic Drug Development

Advanced Therapeutics, EarlyView.
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn, Seonmin Choi, Minju Kim, Zachary Estlack, Daniel Brown, Jaehong Key, Young Joon Seo, Jungkyu Kim   +7 more
wiley   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Concomitant Case of Primary Biliary Cirrhosis and Autoimmune Hemolityc Anemia Responding to Corticosteroid and Ursodeoxycholic Acid in Young Woman

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2016
Primary biliary cirrhosis (PBC) is an autoimmune liver disease of unknown etiology and is characterized by chronic progressive cholestasis with destruction of the small intrahepatic bile ducts and associated most commonly with antimitochondrial ...
Susanto H Kusuma, Fardah Akil, Amelia Rifai, Rini R Bachtiar, Numan AS Daud, AM Luthfi Parewangi   +5 more
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