Results 81 to 90 of about 522,558 (297)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Corticosteroids for hospitalized patients with mild to critically-ill COVID-19: A multicenter, retrospective, propensity score–matched study [PDF]

, 2020
Satoshi Ikeda, Toshihiro Misumi, Shinyu Izumi, Keita Sakamoto, Naoki Nishimura, Shosei Ro, Koichi Fukunaga, Satoshi Okamori, Natsuo Tachikawa, Nobuyuki Miyata, Masaharu Shinkai, Masahiro Shinoda, Yasunari Miyazaki, Yuki Iijima, Takehiro Izumo, Minoru Inomata, Masaki Okamoto, Tomoyoshi Yamaguchi, K Iwabuchi, Makoto Masuda, Hiroyuki Takoi, Yoshitaka Oyamada, Shigeki Fujitani, Masamichi Mineshita, Haruyuki Ishii, Atsushi Nakagawa, Nobuhiro Yamaguchi, Makoto Hibino, Kenji Tsushima, Tatsuya Nagai, Satoru Ishikawa, Nobuhisa Ishikawa, Yasuhiro Kondoh, Yoshitaka Yamazaki, Kyoko Gocho, Tomotaka Nishizawa, Akifumi Tsuzuku, Kazuma Yagi, Yuichiro Shindo, Yuriko Takeda, Takeharu Yamanaka, Takashi Ogura   +41 more
openalex   +1 more source

Pharmacology of Corticosteroids for Diabetic Macular Edema

Investigative Ophthalmology and Visual Science, 2018
Purpose Corticosteroids remain the mainstay of treatment for inflammatory diseases almost 80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have been available to treat disease of the anterior segment of the eye,
S. Whitcup, J. Cidlowski, K. Csaky, J. Ambati   +3 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Modalidades terapéuticas con corticosteroides antenatales en el pretérmino Therapeutic modalities with antenatal corticosteroids in preterm delivery

Medisan, 2012
Actualmente, el nacimiento pretérmino es uno de los problemas básicos en la atención perinatal, pues constituye causa de morbilidad, mortalidad y alteraciones del desarrollo en estos infantes.
Danilo Nápoles Méndez, Elizabeth Fernández Díaz, Plácido de la Rosa Blanco   +2 more
doaj  

Immune Effects of Corticosteroids in Sepsis

Frontiers in Immunology, 2018
Sepsis, a life-threatening organ dysfunction, results from a dysregulated host response to invading pathogens that may be characterized by overwhelming systemic inflammation or some sort of immune paralysis.
Nicholas Heming, S. Sivanandamoorthy, P. Meng, Rania Bounab, D. Annane   +4 more
semanticscholar   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Managing eosinophilic esophagitis: challenges and solutions

Clinical and Experimental Gastroenterology, 2016
Nisha A Shah, Dustin M Albert, Noah M Hall, Fouad J Moawad Department of Medicine, Gastroenterology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA Abstract: Eosinophilic esophagitis (EoE) is a chronic and ...
Shah NA, Albert DM, Hall NM, Moawad FJ
doaj  

Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review)

Oftalʹmologiâ, 2016
Eye inflammation can be caused by different factors — allergies, infection, trauma (including surgery). It can have severe complications, last even after elimination the reason and cause the visual impairment as an outcome.
E. A. Spiridonov
doaj   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source