Results 31 to 40 of about 73,089 (266)

Biotransformation of Cortisone with Rhodococcus rhodnii: Synthesis of New Steroids

Molecules, 2021
Cortisone is a steroid widely used as an anti-inflammatory drug able to suppress the immune system, thus reducing inflammation and attendant pain and swelling at the site of an injury.
Federico Zappaterra, Stefania Costa, Daniela Summa, Valerio Bertolasi, Bruno Semeraro, Paola Pedrini, Raissa Buzzi, Silvia Vertuani   +7 more
doaj   +1 more source

Avenues of future research in homotransplantation of the liver with particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing [PDF]

, 1966
Three general areas of research which bear on the developing field of liver transplantation are reviewed. These are: (1) the prospects of obtaining better immunosuppression with particular reference to heterologous antilymphocyte serum; (2) the possible ...
Anderson, Bibler, Eiseman, Gray, Halgrimson, Hill, Jeejeebhoy, Marchioro, Mikaeloff, Monaco, Monaco, Norman, Patrick, Rich, Robert J. McCardle, Sacks, Starzl, Starzl, Starzl, Starzl, Steinberg, Tanous D. Faris, Thaler, Thomas E. Starzl, Thomas L. Marchioro, Vang, Waksman, Woodruff, Woodruff, Woodruff, Woodruff, Yoji Iwaski   +31 more
core   +1 more source

Of 11 candidate steroids, corticosterone concentration standardized for mass is the most reliable steroid biomarker of nutritional stress across different feather types

Ecology and Evolution, 2019
Measuring corticosterone in feathers has become an informative tool in avian ecology, enabling researchers to investigate carry‐over effects and responses to environmental variability.
Alexis Will, Katherine Wynne‐Edwards, Ruokun Zhou, Alexander Kitaysky   +3 more
doaj   +1 more source

Δ1-Dehydrogenation and C20 Reduction of Cortisone and Hydrocortisone Catalyzed by Rhodococcus Strains

Molecules, 2020
Prednisone and prednisolone are steroids widely used as anti-inflammatory drugs. Development of the pharmaceutical industry is currently aimed at introducing biotechnological processes and replacing multiple-stage chemical syntheses.
Stefania Costa, Federico Zappaterra, Daniela Summa, Bruno Semeraro, Giancarlo Fantin   +4 more
doaj   +1 more source

Consumption of Pomegranate Juice Attenuates Exercise-Induced Oxidative Stress, Blood Pressure and Urinary Cortisol/Cortisone Ratio in Human Adults [PDF]

, 2016
Oxidative stress is exacerbated in overweight and obese individuals after acute exercise compared with their non-obese counterparts. Antioxidant supplementation of the diet may be one intervention to reduce exercise-induced oxidative stress in this ...
Al-Dujaili, Emad, Good, Gillian, Tsang, Catherine   +2 more
core   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Simultaneous Measurement of Cortisol, Cortisone, Dexamethasone and Additional Exogenous Corticosteroids by Rapid and Sensitive LC–MS/MS Analysis

Molecules, 2022
The simultaneous measurement of dexamethasone and cortisol has proven the ability to increase the diagnostic performance of the overnight dexamethasone-suppression test.
Federico Ponzetto, Mirko Parasiliti-Caprino, Fabio Settanni, Antonello Nonnato, Giulio Mengozzi, Ezio Ghigo, Roberta Giordano   +6 more
doaj   +1 more source

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]

, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
1994 Effect of corticosteroids for fetal maturation on perinatal outcomes, Alkalay, Anderson, Andrews, Arlt, Arnold, Asa, Ashwood, Audus, Baker, Ballabh, Ballard, Ballard, Bamberger, Banks, Banks, Barbazanges, Battin, Baulieu, Benassayag, Benediktsson, Bertram, Bettendorf, Blanford, Blettner, Blumenfeld, Bolt, Bolt, Bradley, Bresson, Brosnan, Brown, Burlet, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buske-Kirschbaum, Buttgereit, Carroll, Cattarelli, Charmandari, Christopher Pryce, Chrousos, Cintra, Clifton, Cole, Condon, Crowley, Crowley, Cummings, Czock, Dalziel, Davis, Davis, Dawes, De Kloet, De Kloet, de Kloet, De Kloet, de Kloet, de Weerth, Dean, Dean, Diederich, Diego, Dobbing, Doyle, Dörr, Dörr, Dwan, Easterbrook, Ebrecht, Felszeghy, Fiad, Ford, French, French, Fries, Gatelais, Gayrard, Gennser, Giannakoulopoulos, Giannakoulopoulos, Gibbs, Gitau, Gitau, Glover, Goland, Grier, Grossmann, Gunther Meinlschmidt, Gutteling, Haley, Hanna, Hauser, Haussmann, Heckmann, Heim, Herman, Hingre, Holsboer, Högger, Ioannidis, Jahnukainen, Jaquier, Jeffray, Jobe, Jüni, Kairalla, Kajantie, Kajantie, Kalabis, Kalabis, Kamphuis, Kanitz, Kapoor, Kapoor, Karemaker, Kari, Karlsson, Karssen, Kauppila, Kavelaars, Keene, Kirschbaum, Klemcke, Kononen, Korte, Krauer, Lee, Lee, Lee, Levine, Levitt, Liggins, Liggins, Lindh, Lindsay, Little, Loebstein, MacArthur, Macnaughton, Manabe, Marinoni, Marion Tegethoff, Mark, Mark, Matthews, McAlister, Meadow, Mears, Meijer, Melby, Mesiano, Miller, Modi, Moss, Muneoka, Murphy, Murphy, Murphy, Murphy, National Institutes of Health Consensus Development Panel, Nelson, Nelson, Ng, Ng, Ng, Ng, Ng, Ng, Ng, Noguchi, Nomura, Noorlander, Nordenström, Nykänen, O'Regan, O'Shea, Oelkers, Ohrlander, Ohrlander, Oken, Olufemi, Osathanondh, Owen, Ozawa, Pacheco, Paddock, Parker Jr, Parker Jr, Patel, Peets, Pepe, Pepe, Petersen, Petersen, Petraglia, Petropoulos, Phillips, Pryce, Pryce, Reichardt, Reis, Rizvi, Roberts, Rocci Jr, Rosati, Samtani, Sandesh Kiran, Sapolsky, Sánchez, Schatz, Schwab, Schwab, Seckl, Seckl, Seckl, Serón-Ferré, Shulman, Sippell, Sloboda, Speirs, Speiser, Stein, Streeten, Stroup, Sucheston, Sun, Sybulski, Szabó, Taylor, Tenhola, Teramo, Terrone, Terrone, Thliveris, Trestman, Tsigos, Uhr, Uno, van der Heide-Jalving, Van Hoof, van Runnard Heimel, van Runnard Heimel, Veldhuis, Veldhuis, Vogl, Walters, Watterberg, Welberg, White, Whittaker, Wilson, Wittekind, Yates, Yeh, Yeh   +257 more
core   +2 more sources

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source