Results 31 to 40 of about 38,922 (222)
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Advanced Science, EarlyView.Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker +17 more
wiley +1 more source
Sham-Chewing in Sows Is Associated With Decreased Fear Responses in Their Offspring
Frontiers in Veterinary Science, 2019 We hypothesized that sham-chewing expressed by the dam during gestation affects fetus programming. The goal of this study was to assess the effects of maternal sham-chewing on offspring welfare indicators, such as behavior and physiology.
Patricia Tatemoto +3 more
doaj +1 more source
The Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations
, 2016 Cortisone is an injected anti-inflammatory drug that can cause painful side effects known as "steroid flares" which are caused by cortisone crystallizing at the injection site.
Hub, Jochen S. +3 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
, 2019 Objective:Rotator cuff tendon pathologies are the most frequently diagnosed disease group among the causes of shoulder pain. The aim of this study was to compare the results of platelet-rich plasma (PRP) and cortisone treatments applied to patients who ...
Volkan Subaşı
core +1 more source
Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1:physiological regulator and pharmacological target for energy partitioning [PDF]
, 2007 The major glucocorticoid in man, cortisol, plays important roles in regulating fuel metabolism, energy partitioning and body fat distribution.
Walker, Brian R
core +1 more source
Home waking salivary cortisone to screen for adrenal insufficiency [PDF]
, 2023 BACKGROUND Worldwide, adults and children are at risk of adrenal insufficiency as a result of adrenal suppression from use of anti-inflammatory glucocorticoids and opiates, as well as infectious diseases.
Dixon, S. +10 more
core +1 more source
Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report
Head &Neck, EarlyView.ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann +3 more
wiley +1 more source
Glucocorticoids in hair in relation to cardiometabolic risk markers
European Journal of Psychotraumatology, 2012 Altered long-term secretion of glucocorticoid hormones is believed to play a pivotal role in linking chronic stress to cardiometabolic risk. Despite experimental data supporting this link, previous epidemiological field studies have often yielded ...
Tobias Stalder +3 more
doaj +1 more source