Results 71 to 80 of about 73,089 (266)

Steroid Hormones Are Potent and Putatively Endogenous Activators of Human Bitter Taste Receptors

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
Human bitter taste receptors are not only involved in sensing tastants within the oral cavity but also play crucial roles in internal tissues of the body. The current report identifies numerous structurally and functionally diverse steroid hormones as activators of the two human bitter taste receptors, TAS2R14 and TAS2R46.
Tatjana Lang   +4 more
wiley   +1 more source

Glucocorticoids in hair in relation to cardiometabolic risk markers

open access: yesEuropean Journal of Psychotraumatology, 2012
Altered long-term secretion of glucocorticoid hormones is believed to play a pivotal role in linking chronic stress to cardiometabolic risk. Despite experimental data supporting this link, previous epidemiological field studies have often yielded ...
Tobias Stalder   +3 more
doaj   +1 more source

Substructure Discovery Using Minimum Description Length and Background Knowledge [PDF]

open access: yes, 1994
The ability to identify interesting and repetitive substructures is an essential component to discovering knowledge in structural data. We describe a new version of our SUBDUE substructure discovery system based on the minimum description length ...
Cook, D. J., Holder, L. B.
core   +3 more sources

Efficient in vivo targeting of the myocardial scar using Moloney murine leukaemia virus complexed with nanoparticles

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The complexation of Moloney murine leukaemia virus (MMLV) with magnetic nanoparticles (MNP) greatly enhanced the transduction of (myo)fibroblasts (FB), when applied in a magnetic field, both in vitro and in vivo in cryoinjured mice.
Timo Mohr   +11 more
wiley   +1 more source

Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11[beta]-hydroxysteroid dehydrogenase 1 [PDF]

open access: yes, 2008
Intracellular glucocorticoid reactivation is catalyzed by 11[beta]-hydroxysteroid dehydrogenase 1 (11[beta]-HSD1), which functions predominantly as a reductase in cells expressing hexose-6-phosphate dehydrogenase (H6PDH).
Alex Odermatt   +4 more
core   +1 more source

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa   +10 more
wiley   +1 more source

A Case of Worsened Refractory Ascites due to Prednisolone Administration for Stricture Prevention after Endoscopic Submucosal Dissection for Extensive Early Esophageal Cancer: Case Report and Literature Review

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer, even in patients with liver cirrhosis (LC). Corticosteroids, administered orally or by local injection, are often used to prevent post‐ESD esophageal stricture. However, their safety in patients with decompensated LC and refractory ascites remains unclear. A man
Yuki Tamura   +9 more
wiley   +1 more source

The role of adrenocortical steroids in reversing established homograft rejection [PDF]

open access: yes, 1964
Renal homotransplantation was performed in 8 dogs. Antirejection therapy with azathioprine (BW 57-322, Imuran) was given in doses of 2 to 7.5 mg. per kilogram per day.
Axtell, HK   +4 more
core  

Patient Perspectives of Early Interventions for Healthy Ageing in General Practice: A Qualitative Study

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 1, March 2026.
ABSTRACT Objective As the population ages more people are experiencing chronic conditions, placing substantial burden on the healthcare system. General practice plays a crucial role in managing chronic health conditions and early interventions to support healthy ageing.
Heather Block   +4 more
wiley   +1 more source

Stress Induced Hormone and Neuromodulator Changes in Menopausal Depressive Rats

open access: yesFrontiers in Psychiatry, 2018
Objective: Previously, we showed that neuromodulators are important factors involved in depression, here we aim to further investigate the interactions between neuromodulators and sex hormone involved in menopause related depression in rats.Methods ...
Simeng Gu   +7 more
doaj   +1 more source

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