Results 71 to 80 of about 1,929 (210)

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

Environmental and Molecular Mutagenesis, Volume 66, Issue S2, Page 47-57, December 2025.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li, Jiri Aubrecht, Tatyana Y. Doktorova, Danyel Jennen, J. Christopher Corton, Roland Froetschl, Roman Mezencev, Carole L. Yauk   +7 more
wiley   +1 more source

Nomenclature and typification of sectional names in Carex (Cyperaceae)

TAXON, Volume 74, Issue 6, Page 1543-1568, December 2025.
Abstract This paper presents an updated survey of all the published names at the section rank in Carex and its formerly accepted satellite genera. We included related names at other ranks when relevant. We address validity, legitimacy, priority, typification, and – if relevant – synonymy.
Pedro Jiménez‐Mejías, James L. Reveal, Santiago Martín‐Bravo, Juan Carlos Zamora, Isabel Larridon, Anton A. Reznicek, Robert F.C. Naczi   +6 more
wiley   +1 more source

A novel method for quantifying the biomechanical parameters of orbital soft tissue using a corneal dynamic scheimpflug analyser: a retrospective study

BMC Ophthalmology, 2019
Background To demonstrate that the Corvis ST could be used to quantify the biomechanical parameters of the orbital soft tissues by measuring and comparing whole eye movement (WEM) using the Corvis in normal eyes and in eyes of patients with Graves ...
Ho Sik Hwang, Eun Chul Kim, Man Soo Kim, Suk-Woo Yang   +3 more
doaj   +1 more source

Nanomaterial‐Based Precision Medicine for Breast Cancer Diagnosis and Treatment

ChemNanoMat, Volume 11, Issue 11, November 2025.
This research emphasizes the use of targeted precision medicine in the treatment of breast cancer. Through the integration of diagnosis and therapeutic delivery, nanocarriers are designed to selectively target cancer cells, preserving healthy tissue, thereby improving treatment effectiveness and reducing side effects.
Tanaka Ndongwe, Xavier Siwe Noundou, Gauta Gold Matlou, Stéphanie Bessoles, Johanne Seguin, Cyrille Richard, Nathalie Mignet, Yohann Corvis, Bwalya Angel Witika   +8 more
wiley   +1 more source

Regional corneal biomechanics assessment as a function of age using Strain–Stress Index maps

Ophthalmic and Physiological Optics, Volume 45, Issue 7, Page 1773-1779, November 2025.
Abstract Purpose To gain a better understanding of corneal Stress–Strain Index (SSI) maps in healthy eyes and to determine their changes with age. Method The eyes of 72 participants (age 43.1 ± 20.9 years, 69.5% female) were included in the analysis, considering the left and right eyes separately.
Vahoura Tahsini, Marta Jiménez‐García, Ahmed Makarem, Ahmed Elsheikh, Philippe Büchler, Sabine Kling, Jos J. Rozema   +6 more
wiley   +1 more source

Evaluating the Genotoxicity and Mutagenicity of Food Contaminants: Acrylamide, Penitrem A, and 3‐Acetyldeoxynivalenol in Individual and Combined Exposure In Vitro

Journal of Applied Toxicology, Volume 45, Issue 9, Page 1750-1760, September 2025.
ABSTRACT This study aimed to evaluate the genotoxic effects of food contaminants exposure in human neuroblastoma SH‐SY5Y cells using the micronucleus (MN) assay and Ames test. Acrylamide (AA), penitrem A (PEN A), and 3‐acetyldeoxynivalenol (3‐ADON) were tested both individually and in combination.
Luna Bridgeman, Cristina Juan, Houda Berrada, Isabelle Severin, Ana Juan‐García   +4 more
wiley   +1 more source

Effect of intravitreal bevacizumab injection on corneal in vivo biomechanics: A pilot study

Journal of Ophthalmic & Vision Research, 2019
Purpose: To evaluate the effect of intravitreal bevacizumab (IVB) injection on corneal biomechanical parameters as measured by the ocular response analyzer (ORA) and Corneal Visualization Scheimpflug Technology (CorVis).
Nasser Shoeibi, Mohammad-Reza Ansari-Astaneh, Mohammad Reza Sedaghat, Saeed Shokoohi Rad   +3 more
doaj   +1 more source

Minimally Invasive Glaucoma Surgery Procedure in the Human Eye. A Fluid Structure Interaction Study

International Journal for Numerical Methods in Biomedical Engineering, Volume 41, Issue 7, July 2025.
The implantation of a microstent for glaucoma surgery has been successfully simulated for the first time. A Fluid‐Structure Interaction (FSI) simulation is introduced to model aqueous humor flow dynamics post‐surgery, enabling a detailed analysis of the microstent's interaction with ocular tissues and fluids.
Elena Redaelli, Letizia Maria Perri, Begoña Calvo, Jorge Grasa, Giulia Luraghi   +4 more
wiley   +1 more source

Application of the Brillouin Optical Scanning System in the Regional Corneal Biomechanical Evaluation of Keratoconus and Its Correlation with Corvis ST Parameters

Bioengineering
(1) Background: The early diagnosis of keratoconus is critical for prognosis. Traditional methods like ORA and Corvis ST measure overall corneal biomechanics but lack regional specificity and are affected by intraocular pressure.
Qiuruo Jiang, Yichen Sun, Zhanhao Gu, Lumeng Wang, Yiqiang Wu, Jialu Chen, Zhiyi Chen, Xiaobo Zheng, Shihao Chen   +8 more
doaj   +1 more source

Review of preoperative tomographic and biomechanical corneal assessment for refractive surgery

Taiwan Journal of Ophthalmology
Screening prior to laser refractive surgery is important to detect abnormal preoperative topography, which is a significant risk factor for developing postoperative iatrogenic corneal ectasia.
Elizabeth Wen Ling Lim, Li Lim
doaj   +1 more source