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Corynebacterium diphtheriae [PDF]
Corynebacterium diphtheriae was first observed by Klebs in 1883 and was cultivated a year later by Loeffler, whose description in 1884 of the causative organism of diphtheria remains a standard. Diphtheria was a life-threatening disease throughout the world until the therapeutic use of antitoxin and the use, as a public health measure, of childhood ...
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Re-emergence of Corynebacterium diphtheriae [PDF]
Diphtheria is re-emerging in Europe. A total of 36 cases were reported in Europe in 2015 versus 53 cases between 2000 and 2009.We report two cases of Corynebacterium diphtheriae infection in a French hospital in 2016: a cutaneous infection with negative toxin testing in a French traveller, and a respiratory diphtheria carriage with positive toxin ...
Scheifer, Carole +8 more
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Corynebacterium ulcerans cutaneous diphtheria
We describe the case of a patient with cutaneous diphtheria caused by toxigenic Corynebacterium ulcerans who developed a right hand flexor sheath infection and symptoms of sepsis such as fever, tachycardia, and elevated C-reactive protein, after contact with domestic cats and dogs, and a fox.
Moore, LS +5 more
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NovelCorynebacterium diphtheriaein Domestic Cats [PDF]
Novel nontoxigenic Corynebacterium diphtheriae was isolated from a domestic cat with severe otitis. Contact investigation and carrier study of human and animal contacts yielded 3 additional, identical isolates from cats, although no evidence of zoonotic transmission was identified.
Aron J. Hall +14 more
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Diphtheria toxin is one of the best investigated bacterial toxins and the major virulence factor of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains. However, also diphtheria toxin-free strains of these two species can cause severe infections in animals and humans, indicating the presence of additional virulence factors.
Dulanthi Weerasekera +5 more
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Corynebacterium diphtheriae endocarditis
The authors report the case of a 69-year-old man with an acute toxemic and febrile syndrome. Immediately after admission, the patient’s mental status rapidly deteriorated. A faint mitral systolic murmur was detected and splenomegaly was observed on ultrasound examination.
Fernando Peixoto Ferraz de Campos +4 more
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Cell Structure of Corynebacterium diphtheriae [PDF]
SUMMARY: When examined by phase-contrast microscopy living diphtheria bacilli generally appear fairly transparent. They are sometimes unicellular but are frequently divided into compartments by readily visible cross-septa. In gravis and mitis strains the cross septa are usually few in number and the compartments long, but in intermedius strains there ...
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