Results 1 to 10 of about 542,716 (249)
Clinical and Vaccine Immunology, 2011 A nonspecific binding of antibodies to diphtheria toxin, especially in adult serum samples, was observed in our diphtheria-tetanus-pertussis multiplex immunoassay (DTaP4 MIA). This can be significantly reduced by the use of diphtheria toxoid, achieving a
P. V. van Gageldonk +3 more
semanticscholar +2 more sources
Postresuscitative Myocardial Impact of Anatoxin Preimmunization
Общая реаниматология, 2007 Objective: to study the impact of preimmunization with tetanus, diphtheria, and staphylococcal anatoxins on postresuscitative myocardial pathology.Materials and methods.
D. A. Yenikeyev +4 more
doaj +1 more source
Diphtheria toxin-binding glycoproteins on hamster cells: candidates for diphtheria toxin receptors [PDF]
Infection and Immunity, 1979 Diphtheria toxin-binding glycoproteins of high molecular weight (greater than 100,000) were identified on the surface of lymph node and thymus cells from hamsters, a diphtheria toxin-sensitive species. These diphtheria toxin-binding glycoproteins also interacted with CRM197 protein, which possesses toxin-blocking activity, but not with diphtheria ...
R L, Proia, L, Eidels, D A, Hart
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BMC Microbiology, 2012 Corynebacterium ulcerans can cause a diphtheria-like illness, especially when the bacterium is lysogenized with a tox gene-carrying bacteriophage that produces diphtheria toxin. Acquisition of toxigenicity upon phage lysogenization is a common feature of
T. Sekizuka +8 more
semanticscholar +1 more source
Discover ChemistryDiphtheria toxin, a major virulence factor of Corynebacterium diphtheriae, continues to pose significant therapeutic challenges in the face of antimicrobial resistance. Flavonoids, owing to their structural diversity and bioactivity, represent attractive
Chidi Edbert Duru +4 more
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Functional verification of the diphtheria toxin A gene in a recombinant system
Journal of Animal Science and Biotechnology, 2012 Diphtheria toxin A (DTA), a segment of the diphtheria toxin (tox), inhibits protein synthesis in cells. When released from a cell, DTA is nontoxic and cannot enter other cells independently without the help of diphtheria toxin B.
Zhang Jingfeng +6 more
doaj +1 more source
Observations on the Structure of Diphtheria Toxin
Journal of Biological Chemistry, 1971 Diphtheria toxin is synthesized as a single polypeptide chain with a molecular weight of about 62,000. After being secreted it may be partially digested by proteolytic enzymes released from the bacterial cells into the culture medium and purified preparations of toxin usually contain some of the proteolytic breakdown products.
D M, Gill, L L, Dinius
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Nature CommunicationsCorynebacterium ulcerans is an emerging zoonotic pathogen which causes diphtheria-like infections. Although C. ulcerans is found in multiple domestic and wild animal species, most human cases are linked with pets.
Chiara Crestani +7 more
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Sri Lankan Journal of Infectious Diseases, 2011 Diphtheria is a nearly eradicated disease in Sri Lanka. After introduction of EPI vaccination program in 1978 childhood diphtheria has been eradicated.
Rohitha Jayamaha
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Development of a diphtheria toxin based anti-porcine CD3 recombinant immunotoxin
Bioconjugate chemistry, 2011 Anti-CD3 immunotoxins, which induce profound but transient T cell depletion in vivo by inhibiting eukaryotic protein synthesis in CD3+ cells, are effective reagents in large animal models of transplantation tolerance and autoimmune disease therapy.
Zhi-Rui Wang +8 more
semanticscholar +1 more source