Results 41 to 50 of about 404,518 (216)
DETERMINATION OF REGIMES FOR DIPHTHERIA EXOTOXIN MODIFICATION BY CHEMICAL AND PHYSICOCHEMICAL METHODS [PDF]
Annals of Mechnikov's Institute, 2011 The possibility of diphtheria toxoid obtaining using chemical (amino sugars, organic acids) and physicochemical (amino sugars, organic acids, ultrasound, temperature) factors was studied.
Antusheva T.I. +7 more
doaj
Novelty in Biomedicine, 2018 Background: Targeted cancer therapies have played a great role in the treatment of malignant tumors, in the recent years. Among these therapies, targeted toxin therapies such as immunotoxins, has improved the patient’s survival rate by minimizing the ...
Sahel Amoozadeh +4 more
doaj +1 more source
ACTIVE IMMUNITY PRODUCED BY SO CALLED BALANCED OR NEUTRAL MIXTURES OF DIPHTHERIA TOXIN AND ANTITOXIN
Journal of Experimental Medicine, 1909 The foregoing and earlier data taken together demonstrate that an active immunity lasting several years can be produced in guinea-pigs, by the injection of toxin-antitoxin mixtures which have no recognizable harmful effect either immediate or remote ...
Theobald. Smith
semanticscholar +1 more source
Advanced Science, EarlyView.Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao +19 more
wiley +1 more source
Toxins, 2015 The cholix toxin gene (chxA) was first identified in V. cholerae strains in 2007, and the protein was identified by bioinformatics analysis in 2008. It was identified as the third member of the diphtheria toxin group of mono-ADP-ribosyltransferase toxins
Miguel R. Lugo, A. Rod Merrill
doaj +1 more source
Nature Communications, 2021 Reported incidence of pertussis in the European Union (EU) and the European Economic Area (EEA) varies and may not reflect the real situation, while vaccine-induced protection against diphtheria and tetanus seems sufficient.
G. Berbers +44 more
semanticscholar +1 more source
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Angewandte Chemie International Edition, EarlyView.Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
SYNTHESIS AND CHARACTERIZATION OF POLY(D,L-LACTIC-CO-GLYCOLIC)ACID MICROPARTICLES LOADED BY DIPHTHERIA TOXOID [PDF]
Biotechnologia Acta, 2018 The aim of the study was to synthesize poly(D,L-lactide-co-glycolide) particles — PLGA and obtain their complexes with a non-toxic diphtheria toxin recombinant fragment subunit B fused with enhanced green fluorescent protein EGFP-SubB; to characterize ...
T. O. Chudina +2 more
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Data in Brief, 2022 Corynebacterium diphtheriae (C. diphtheriae) is the causative agent of diphtheria. The main virulence factor of C. diphtheriae is diphtheria toxin, which is encoded by the tox gene and regulated by the dtxR gene.
Vivi Setiawaty +11 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse +4 more
wiley +1 more source