Results 31 to 40 of about 1,931 (109)

A solid approach to biopharmaceutical stabilisation [PDF]

, 2018
Ensilication is a technology we developed that can physically stabilise proteins in silica without use of a pre-formed particle matrix. Stabilisation is done by tailor fitting individual proteins with a silica coat using a modified sol-gel process. Biopharmaceuticals, for example, liquid-formulated vaccines with adjuvants, have poor thermal stability ...
arxiv   +1 more source

Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration

Case Reports in Dermatology, 2017
In the context of the European migrant crisis, more and more cases of cutaneous diphtheria are seen. A typical presentation includes painful cutaneous ulcerations with grayish-whitish pseudomembranes.
Antonios G.A. Kolios, Antonio Cozzio, Annelies S. Zinkernagel, Lars E. French, Thomas M. Kündig   +4 more
doaj   +1 more source

Molecular characterization and phylogenetic analysis of the first Corynebacterium rouxii strains isolated in Brazil: a recent member of Corynebacterium diphtheriae complex

BMC Genomic Data, 2023
Background Corynebacterium diphtheriae complex was formed by the species C. diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis in the recent past. In addition to C. diphtheriae, C. ulcerans and C.
Juliana Nunes Ramos, Max Roberto Batista Araújo, Paulo Victor Pereira Baio, Lincoln Oliveira Sant’Anna, João Flávio Carneiro Veras, Érica Miranda Damásio Vieira, Mireille Ângela Bernardes Sousa, Carlos Henrique Camargo, Cláudio Tavares Sacchi, Karoline Rodrigues Campos, Marlon Benedito Nascimento Santos, Sérgio Bokermann, Luige Biciati Alvim, Louisy Sanches dos Santos, Ana Luiza de Mattos-Guaraldi, Verônica Viana Vieira   +15 more
doaj   +1 more source

Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report

Frontiers in Medicine, 2023
Here we document a rare, acute, infection caused by non-toxigenic Corynebacterium diphtheriae and the resulting unique and severe clinical sequelae.
George V. Alvarez, Deborah D. Rupert, Samantha Sinclair, Santiago J. Miyara, Santiago J. Miyara, Sara Guevara, Peter Shih, Cynthia Hoey   +7 more
doaj   +1 more source

Diphtheria diagnostic capacity in the Western Pacific Region

Western Pacific Surveillance and Response, 2019
Diphtheria is an acute infectious disease affecting the upper respiratory tract and occasionally the skin and is caused by the action of diphtheria toxin produced by Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium ...
Santosh Gurung, Amy Trindall, Lucy Reeve, Adroulla Efstratiou, Varja Grabovac   +4 more
doaj   +1 more source

Non-toxigenic penicillin-resistant cutaneous C. diphtheriae infection: A case report and review of the literature

Journal of Infection and Public Health, 2015
Summary: Here, we report a case of non-toxigenic Corynebacterium diphtheriae in a previously healthy 14-year-old girl that was acquired in Ethiopia and presented locally. This is the first clinical case of penicillin-resistant C.
Rosemarie Philippa FitzGerald, Andrew J. Rosser, Dona Nelun Perera   +2 more
doaj  

Bacteremia complicated with pneumonia caused by Corynebacterium diphtheriae

Infectious Medicine, 2022
Due to the use of vaccines, infections caused by Corynebacterium diphtheriae are now rare. Here we describe a case of bacteremia complicated with pneumonia caused by C. diphtheriae in a 69-year-old male patient.
Xiaojun Zhou, Xuebing Wang, Hua Wu, Meihui Huang, Shaoling Wang, Xuming Wang, Haijian Zhou   +6 more
doaj  

Corynebacterium diphtheriae infection as a dermatological problem – case report and review of the literature

Przegląd Dermatologiczny, 2019
We report the case of a 36-year-old male patient with alcohol dependence syndrome who was admitted to the Dermatology Unit with erythroderma of unknown aetiology persisting for approximately 2 years. A considerable degree of deformity and ulceration were
Paulina Cieplewicz, Marta Szymoniak-Lipska, Magdalena Jałowska, Adriana Polańska, Monika Bowszyc-Dmochowska, Hanna Tomczak, Ryszard Żaba, Zygmunt Adamski   +7 more
doaj   +1 more source

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Nature Communications, 2021
Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and ...
Robert C. Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja   +15 more
doaj   +1 more source

Proteomics of Toxigenic Corynebacteria

Proteomes, 2023
Within the genus Corynebacterium, six species are potential carriers of the tox gene, which encodes the highly potent diphtheria exotoxin: Corynebacterium diphtheriae, Corynebacterium belfantii, Corynebacterium rouxii, Corynebacterium ulcerans ...
Andreas Burkovski
doaj   +1 more source