Results 51 to 60 of about 24,074 (246)
BMC Research Notes, 2019 Objectives In frame of a study to characterize the interaction of human macrophage-like cells with pathogenic corynebacteria, Corynebacterium diphtheriae and Corynebacterium ulcerans, live cell imaging experiments were carried out and time lapse ...
Dulanthi Weerasekera +3 more
doaj +1 more source
Direct PCR: Alternative Diagnostic Method for Diagnosis of Diphtheria Rapidly, Easily and Cost Effective [PDF]
, 2013 Some diseases require immediate and appropriate treatment to decrease the fatality risk patients incident, for example diphtheria. Time to help patients is very crucial since delay of therapy may increase the mortality cases up to 20 times.
Karuniawati, A. (Anis) +5 more
core +2 more sources
Acta Paediatrica, EarlyView.ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad +6 more
wiley +1 more source
Frontiers in BacteriologyIntroductionDiphtheria is a potentially fatal disease that still causes deaths mainly in unvaccinated children. Over the last decades, the incidence of this disease has reduced drastically in face to the increase in vaccination coverage.
Sérgio Bokermann +10 more
doaj +1 more source
Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia
Emerging Infectious Diseases, 2017 By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria.
Christine J. Doyle +5 more
doaj +1 more source
Genomic analyses reveal two distinct lineages of Corynebacterium ulcerans strains [PDF]
, 2018 Corynebacterium ulcerans is an important zoonotic pathogen which is causing diphtheria-like disease in humans, globally. In this study, the genomes of three recently isolated C.
Burkovski, Andreas +8 more
core +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
The FEBS Journal, EarlyView.During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Microbe profile : Corynebacterium diphtheriae - an old foe always ready to seize opportunity [PDF]
, 2018 Diphtheria AB toxin mode of action. The diphtheria AB exotoxin consists of two polypeptide chains - A and B which are linked by a disulfide bridge. The B chain binds to the heparin-binding epidermal growth factor precursor on eukaryotic cells and is ...
Hoskisson, Paul A.
core +1 more source
Public Health Challenges, Volume 5, Issue 2, June 2026.Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley +1 more source
Comparative genomic analyses reveal a lack of a substantial signature of host adaptation in Rhodococcus equi (‘Prescottella equi’) [PDF]
, 2013 Rhodococcus equi (‘Prescottella equi’) is a pathogenic actinomycete primarily infecting horses but has emerged as an opportunistic human pathogen. We have sequenced the genome of the type strain of this species, R.
Arruda +35 more
core +1 more source