Results 61 to 70 of about 35,864 (201)

Corynebacterium diphtheriae infection as a dermatological problem – case report and review of the literature

Przegląd Dermatologiczny, 2019
We report the case of a 36-year-old male patient with alcohol dependence syndrome who was admitted to the Dermatology Unit with erythroderma of unknown aetiology persisting for approximately 2 years. A considerable degree of deformity and ulceration were
Paulina Cieplewicz, Marta Szymoniak-Lipska, Magdalena Jałowska, Adriana Polańska, Monika Bowszyc-Dmochowska, Hanna Tomczak, Ryszard Żaba, Zygmunt Adamski   +7 more
doaj   +1 more source

Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae

Nature Communications, 2021
Cases of diphtheria have increased in recent years. Here, the authors analyse the genomes of 502 Corynebacterium diphtheriae isolates across 16 countries and territories over 122 years, describing an increase in antimicrobial resistance genes and ...
Robert C. Will, Thandavarayan Ramamurthy, Naresh Chand Sharma, Balaji Veeraraghavan, Lucky Sangal, Pradeep Haldar, Agila Kumari Pragasam, Karthick Vasudevan, Dhirendra Kumar, Bhabatosh Das, Eva Heinz, Vyacheslav Melnikov, Stephen Baker, Vartul Sangal, Gordon Dougan, Ankur Mutreja   +15 more
doaj   +1 more source

Effect of Topical Application of Antimicrobial Peptide PL‐5 (Peceleganan) Spray on Mild to Moderate Infection of Diabetic Foot Ulcers: A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial

Journal of Diabetes, Volume 18, Issue 7, July 2026.
Topical PL‐5 spray improves clinical outcomes in mild‐to‐moderate infected diabetic foot ulcers and achieves superior pathogen clearance among drug‐resistant infection subgroups. It represents a promising low‐resistance topical option for managing mild to moderate DFU infections.
Li Qian, Xinjuan Sun, Rourou Chen, Qiuyu Lin, Chen Yu, Guofeng Wang, Wen Hu, Jianfang Che, Aiping Wang, Yuxin Chen, Yu Liu   +10 more
wiley   +1 more source

Isolamento de Corynebacterium diphtheriae de líquido espermático Isolation of Corynebacterium diphtheriae from sperm

Memorias do Instituto Oswaldo Cruz, 1989
Descrevemos o isolamento de Corynebacterium diphtheriae toxígeno de espermocultura. O microrganismo foi identificado pelo teste de fluorescência sob luz ultravioleta, pesquisa da enzima pirazina-carboxilamidase (Pyz), testes de virulência in vitro e in ...
Thaís Lisbôa Machado, Luiz Carlos D. Formiga, Raimundo Diogo Machado, Ruiter R. da Silva   +3 more
doaj   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

Clinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan, Nipun Shrestha, Dhruba Shrestha   +2 more
wiley   +1 more source

Efek Antimikroba Daun Sirih Merah (Piper Crocatum) Terhadap Pertumbuhan Bakteri Corynebacterium Diphtheriae Dan Corynebacterium Striatum Secara In Vitro [PDF]

, 2018
Corynebacterium sp. adalah bakteri yang dapat menjadi patogen berbahaya karena dapat menginfeksi manusia. Corynebacterium sp. yang dapat menyebabkan infeksi adalah Corynebacterium diphtheriae dan Corynebacterium striatum.
Rahayu, Desy Eka
core  

NGS-based phylogeny of diphtheria-related pathogenicity factors in different Corynebacterium spp. implies species-specific virulence transmission

BMC Microbiology, 2019
Background Diphtheria toxin (DT) is produced by toxigenic strains of the human pathogen Corynebacterium diphtheriae as well as zoonotic C. ulcerans and C. pseudotuberculosis.
Alexandra Dangel, Anja Berger, Regina Konrad, Andreas Sing   +3 more
doaj   +1 more source

Integrated Molecular Docking and Gene Expression Analyses Suggest a Potential Interaction Between Diphtheria Toxin and Bcl‐2 in HT‐29 Colorectal Cancer Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan, Tugba Yalcinkaya, Belkis Levent, Ahmet Carhan   +3 more
wiley   +1 more source

Beyond diphtheria toxin: cytotoxic proteins of Corynebacterium ulcerans and Corynebacterium diphtheriae

Microbiology, 2019
Diphtheria toxin is one of the best investigated bacterial toxins and the major virulence factor of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains. However, also diphtheria toxin-free strains of these two species can cause severe infections in animals and humans, indicating the presence of additional virulence factors.
Dulanthi Weerasekera, Jens Möller, Max Edmund Kraner, Camila Azevedo Antunes, Ana Luiza Mattos-Guaraldi, Andreas Burkovski   +5 more
openaire   +2 more sources

Diphtheria Vaccination Coverage and Correlation With Multidimensional Poverty Among Children in Nigeria

Public Health Challenges, Volume 5, Issue 2, June 2026.
Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley   +1 more source