Results 51 to 60 of about 13,650 (259)

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum

Molecular Microbiology, EarlyView.
Iron is essential for life, yet excessive levels can quickly lead to cellular damage via oxidative stress, underscoring the need for global regulators of iron and heme homeostasis. In this study, we present a genome‐wide analysis of the binding patterns of DtxR and HrrA in Corynebacterium glutamicum.
Aileen Krüger, Ulrike Weber, Julia Frunzke   +2 more
wiley   +1 more source

Population genomics and antimicrobial resistance in Corynebacterium diphtheriae [PDF]

Genome Medicine, 2020
AbstractBackgroundCorynebacterium diphtheriae, the agent of diphtheria, is a genetically diverse bacterial species. Although antimicrobial resistance has emerged against several drugs including first-line penicillin, the genomic determinants and population dynamics of resistance are largely unknown for this neglected human pathogen.MethodsHere, we ...
Anne Marie Wehenkel, Leonardo G. Panunzi, Leonardo G. Panunzi, Marina Barros-Pinkelnig, Melanie Hennart, Melanie Hennart, Sylvain Brisse, Julie Toubiana, Julie Toubiana, Xavier Didelot, Edgar Badell, Carla Rodrigues, Annick Carmi-Leroy, Quentin Gaday, Melody Dazas, Sarah L. Baines   +15 more
openaire   +8 more sources

Microbiome and Metaproteome of Craniofacial Implant Regions in Health and Disease

Oral Diseases, EarlyView.
ABSTRACT Background Craniofacial defects from cancer surgery led to functional, aesthetic, and psychological challenges. Rehabilitation with craniofacial implants addresses these issues by improving prosthesis retention through osseointegration and providing predictable cosmetic results. However, maintaining a healthy transcutaneous region is essential
Daniela Lattuf Cortizo, Renato C. V. Casarin, Hélvis E. S. Paz, Camila S. Stolf, Mabelle F. Monteiro, Mônica T. V. Labate, Márcio Z. Casati, Luciano Lauria Dib   +7 more
wiley   +1 more source

Comparative genomic analyses reveal a lack of a substantial signature of host adaptation in Rhodococcus equi (‘Prescottella equi’) [PDF]

, 2013
Rhodococcus equi (‘Prescottella equi’) is a pathogenic actinomycete primarily infecting horses but has emerged as an opportunistic human pathogen. We have sequenced the genome of the type strain of this species, R.
Arruda, Aziz, Aziz, Clark, Darling, Giguere, Goodfellow, Grant, Jones, Jones, Jones, Kedlaya, Kämpfer, Lai, Law, Letek, Letek, Lowder, McLeod, Mohn, Pena-Moctezuma, Prescott, Prescott, Resch, Reumerman, Sangal, Sangal, Segata, Sekine, Takai, Takai, Teufel, Vazquez-Boland, Vera-Cabrera, Vernikos, Yamshchikov   +35 more
core   +1 more source

Severe Pneumonia Caused by Toxigenic Corynebacterium ulcerans Infection, Japan

Emerging Infectious Diseases, 2018
Corynebacterium ulcerans infection was recently recognized as a zoonosis. We present 2 cases of severe pneumonia complicated by diffuse pseudomembrane formation on the bronchus caused by C. ulcerans–producing diphtheria toxin.
Ikkoh Yasuda, Hisayo Matsuyama, Tomoko Ishifuji, Yoshiro Yamashita, Masahiro Takaki, Konosuke Morimoto, Motohiro Sekino, Katsunori Yanagihara, Tatsuya Fujii, Masaaki Iwaki, Akihiko Yamamoto, Koya Ariyoshi, Takeshi Tanaka   +12 more
doaj   +1 more source

The Different Types of Corynebacterium diphtheria [PDF]

Journal of Hygiene, 1933
In 1890 Klein described two types of colony of the diphtheria bacillus on gelatin; one smooth and circular, the other radiating and resembling a daisy. Cowan (1927) observed two types of colony, but one of the types was thought to be due to roughening. Parker (1928) observed three types of colony, some of which were considered ordinary rough variants.
W. H. Fussell, T. V. Cooper, J. Menton, F. W. Duke   +3 more
openaire   +3 more sources

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, Volume 20, Issue 7, Page 710-726, July 2025.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Possible human-to-human transmission of toxigenic Corynebacterium ulcerans [PDF]

, 2015
Toxigenic Corynebacterium ulcerans is an emerging cause of diphtheria. In contrast to the classical diphtheria pathogen C. diphtheriae, human-to-human transmission of this primarily zoonotic pathogen has not been clearly documented.
Hörmansdorfer, S., Konrad, R., Sing, A.
core   +1 more source

ISOLAMENTO DE AMOSTRAS DO COMPLEXO CORYNEBACTERIUM DIPHTHERIAE POTENCIALMENTE TOXINOGÊNICAS DURANTE A PANDEMIA DA COVID-19 NO BRASIL: UM ALERTA À VIGILÂNCIA EPIDEMIOLÓGICA BRASILEIRA

Brazilian Journal of Infectious Diseases, 2023
Introdução/objetivo: A difteria é uma toxiinfecção aguda que se apresenta na forma respiratória e/ou cutânea, e que pode ser fatal devido à ação da toxina diftérica (TD).
Lincoln de Oliveira Sant'Anna, Max Roberto Batista de Araújo, Tayná do Carmo Sant'Anna Cardoso, Fernanda Diniz Prates, Mariana da Cruz Mota, Mireille Ângela Bernardes Sousa, Paula Marcele Afonso Pereira Ribeiro, Ana Luiza de Mattos-Guaraldi, Louisy Sanches dos Santos   +8 more
doaj