Results 81 to 90 of about 13,650 (259)

Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research

Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.
This article provides an overview over antibacterial drugs investigated in the past three decades. Aspects of the compound's origins, their cellular targets, the antibacterial spectrum and proof‐of‐concept in animal studies are covered and current trends are highlighted.
Roderich D. Süssmuth, Marcel Kulike‐Koczula, Peng Gao, Simone Kosol   +3 more
wiley   +1 more source

Isolamento de Corynebacterium diphtheriae de líquido espermático Isolation of Corynebacterium diphtheriae from sperm

Memorias do Instituto Oswaldo Cruz, 1989
Descrevemos o isolamento de Corynebacterium diphtheriae toxígeno de espermocultura. O microrganismo foi identificado pelo teste de fluorescência sob luz ultravioleta, pesquisa da enzima pirazina-carboxilamidase (Pyz), testes de virulência in vitro e in ...
Thaís Lisbôa Machado, Luiz Carlos D. Formiga, Raimundo Diogo Machado, Ruiter R. da Silva   +3 more
doaj   +1 more source

Complexation of CcmB with CcmACD safeguards heme translocation for cytochrome c maturation

mLife, Volume 4, Issue 1, Page 29-44, February 2025.
Abstract Cytochrome c maturation (CCM), a posttranslational modification involving covalent attachment of heme to polypeptides (apocyt c), is essential for the activity and cellular function of cytochromes c. Here, we identify and substantiate CcmB as heme translocase in bacteria.
Yuanyou Xu, Wei Wang, Qianrou Zhang, Sirui Han, Jiahao Wang, Shihua Wu, Haichun Gao   +6 more
wiley   +1 more source

Insights into the flexibility of the domain‐linking loop in actinobacterial coproheme decarboxylase through structures and molecular dynamics simulations

Protein Science, Volume 34, Issue 2, February 2025.
Abstract Prokaryotic heme biosynthesis in Gram‐positive bacteria follows the coproporphyrin‐dependent heme biosynthesis pathway. The last step in this pathway is catalyzed by the enzyme coproheme decarboxylase, which oxidatively transforms two propionate groups into vinyl groups yielding heme b.
Gaurav Patil, Diego Javier Alonso de Armiño, Yirui Guo, Paul G. Furtmüller, Dominika Borek, Dario A. Estrin, Stefan Hofbauer   +6 more
wiley   +1 more source

Identifikasi Temuan Kontak Positif Kasus Kejadian Luar Biasa Difteria di DKI Jakarta [PDF]

, 2013
Rendahnya cakupan imunisasi dasar di DKI Jakarta ini menyebabkan kekhawatiran timbulnya penyakit yang dapat dicegah dengan imunisasi (PD3I) dimana salah satunya adalah difteri.
Amalia, N. (Novi), HP, R. (Rudi), Sariadji, K. (Kambang), Subangkit, S. (Subangkit), Sunarno, S. (Sunarno), Sundari, S. (Sundari)   +5 more
core  

Virulence Factor Genes Detected in the Complete Genome Sequence of Corynebacterium uterequi DSM 45634, Isolated from the Uterus of a Maiden Mare [PDF]

, 2015
The complete genome sequence of the type strain Corynebacterium uterequi DSM 45634 from an equine urogenital tract specimen comprises 2,419,437 bp and 2,163 protein-coding genes.
Jaenicke, Sebastian, Kriete, Martin, Rueckert, Christian, Tauch, Andreas, Winkler, Anika   +4 more
core   +2 more sources

Antibiotic Susceptibility of Zoonotic Bacteria Isolated From Oral Cavities of Indigenous Dogs From Semi‐Urban Areas in Uganda

Veterinary Medicine and Science, Volume 11, Issue 1, January 2025.
Dog bites lead to bacterial infections. Isolation and identification of zoonotic bacterial species from the oral cavities of indigenous dogs using biochemical tests were carried out. The antibiotic susceptibility profile of the commonly identified bacteria species was established using Kirby–Bauer disk diffusion approach.
Paul Mukasa, Patrick Engeu Ogwang, Richard Oriko Owor, Julius B. Lejju, Hannington Gumisiriza, Ibrahim Ntulume, Christopher Adaku   +6 more
wiley   +1 more source

Örjan Ouchterlony and the antigen–antibody double diffusion‐in‐gel: a survey

APMIS, Volume 133, Issue 1, January 2025.
The Swedish scientist Örjan Ouchterlony published four ground‐breaking papers 1948–1966 in Acta Pathol Microbiol Scand where he described a new method of antigen–antibody reactions in gel. He described and defined the ‘reaction of identity’ and ‘reaction of partial identity’ when he used related antigens and ‘reaction of non‐identity’ when he used non ...
Niels Høiby
wiley   +1 more source

Corynebacterium diphtheria, Adhesion, Type and Biofilm Cultures

Эпидемиология и вакцинопрофилактика, 2019
Relevance. It is now known that toxigenic strains of Corynebacterium diphtheriae are capable not only of adhesion, but also of invasion into epithelial cells of the upper respiratory tract.
G. G. Kharseeva, A. A. Alieva, A. V. Chepusova, E. L. Alutina, O. I. Sylka   +4 more
doaj   +1 more source

Mono‐ADP‐Ribosylation of Peptides: An Overview of Synthetic and Chemoenzymatic Methodologies

ChemBioChem, Volume 25, Issue 24, December 16, 2024.
Adenosine diphosphate (ADP)‐ribosylation is a post‐translational modification that regulates key biological processes. It occurs on a wide range of amino acids, including arginine, cysteine, serine, and glutamic acid. Well‐defined ADP‐ribosylated peptides are valuable tools for investigating the structures, mechanisms of action, and interaction ...
Hugo Minnee, Jeroen D. C. Codée, Dmitri V. Filippov   +2 more
wiley   +1 more source