MedComm, Volume 7, Issue 9, September 2026.SPR‐UPLC‐QTOF/MS‐GNPS‐guided screening identified hypermonol J (HPJ) as a high‐affinity TNF‐binding small molecule. HPJ may stabilize TNF dimers, reduce active trimer formation, and suppress TNFR1/NF‐κB signaling, thereby alleviating inflammatory pathology in psoriasis and acute lung injury models.
Yongqi Li +11 more
wiley +1 more source
Acute effects of predominantly inertial load-induced post-activation potentiation on upper-body muscle mechanics: implications for racket sports performance. [PDF]
Front Sports Act LivingKocić Pajić S +5 more
europepmc +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Eight chalcone‐sulfonamide hybrids (12a–h) are synthesized via Claisen–Schmidt condensation and evaluated for antibacterial, antioxidant, and anti‐inflammatory activity. The compounds show potent radical scavenging, strong protein‐denaturation inhibition surpassing diclofenac, and favorable docking against DHPS, myeloperoxidase, COX‐2, and ...
Mlis Belete +5 more
wiley +1 more source
Organizational Support and Job Satisfaction of Nurses in Contemporary Clinical Practice: Indirect Associations Through Distributive Justice and Emotional Exhaustion. [PDF]
Healthcare (Basel)Mamić M +10 more
europepmc +1 more source
Stability studies of cynaropicrin–major sesquiterpene lactone of Cynara cardunculus leaves
Pest Management Science, Volume 82, Issue 9, Page 8820-8830, September 2026.This study investigated its stability under high temperature and pH, mimicking agronomic extremes and under soil context. Bioassays demonstrated that degradation products exhibited higher phytotoxic activity than cynaropicrin and deacylcynaropicrin. This is the first study about cynaropicrin's stability, characterizing degradation products, and their ...
Daniela Rosa +6 more
wiley +1 more source
Programming Multidomain Peptides With Molecular Frustration Into Biomolecular Condensates
Small, Volume 22, Issue 51, 11 September 2026.De novo designed multidomain peptides (MDPs) were used to explore how molecular ordering influences peptide phase behavior. MDPs containing partially folded β‐sheets were found to form biomolecular condensates. This work introduces a new design principle for condensate formation and expand the design space beyond conventional intrinsically disordered ...
Debdatta Das +12 more
wiley +1 more source
Navigating the Impossible Gallbladder: Bailout Strategies and Culture of Safety in Laparoscopic Cholecystectomy. [PDF]
CureusRauf F +7 more
europepmc +1 more source
Cell Proliferation, Volume 59, Issue 9, September 2026.Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
Age-Related Differences in Dietary Intake and Nutritional Status Among Older Adults in Croatia: Results from a National Food Consumption Survey. [PDF]
Epidemiologia (Basel)Šoher L +7 more
europepmc +1 more source