Results 281 to 290 of about 8,710 (316)

Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt   +13 more
wiley   +1 more source

Effective Prevention of Early Childhood Caries in Well-Baby Clinics: Results of a Pragmatic Randomized Trial.

open access: yesCaries Res
van Spreuwel PCJM   +4 more
europepmc   +1 more source

Effects of Different Loading Types on the Validity and Magnitude of Force-Velocity Relationship Parameters. [PDF]

open access: yesSports Health
Jankovic G   +5 more
europepmc   +1 more source

Macrocycles of Saxitoxin: Insights into the Structure of Zetekitoxin AB

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
Synthetic macrocycles of (+)‐saxitoxin, the causative agent of paralytic shellfish poisoning, have been prepared. These are designed to mimic the macrocyclic core of the proposed structure for zetekitoxin AB. Interestingly, these synthetic macrocycles do not form the C12 hydrate as commonly observed in this family of toxins, casting doubt on the ...
Wenyuan Li   +7 more
wiley   +1 more source

Exploring Toxicity of Per- and Polyfluoroalkyl Substances (PFAS) Mixture Through ADMET and Toxicogenomic In Silico Analysis: Molecular Insights. [PDF]

open access: yesInt J Mol Sci
Baralić K   +6 more
europepmc   +1 more source

Chiral Materials from Biomass: 3‐deoxy‐α‐D‐ribono‐1,4‐lactone and 3‐deoxy‐α‐D‐arabino‐1,4‐lactone via the Bromination of Cyrene

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 19, May 27, 2025.
The biomass pyrolysis product levoglucosenone enables the preparation of the feeding modulator 3‐deoxy‐d‐arabino‐1,4‐lactone and the diastereomer 3‐deoxy‐d‐ribono‐1,4‐lactone. The key steps involve a diastereoselective bromination using an enamine bromination‐hydrolysis strategy on the bicyclic ring‐system followed by selective nucleophilic ...
Johannes Puschnig   +2 more
wiley   +1 more source

Optimization of Steroid Photochemistry and Its Application in the Synthesis of 5,6‐Dihydro‐Ophiopogonol A

open access: yesChemistry – A European Journal, Volume 31, Issue 29, May 22, 2025.
Steroid photoreactivity was a major topic in the last century. This study revisits it by exploring the photochemistry of Δ1‐keto‐steroids, offering an efficient method to modify the classic steroid 6/6/6/5 ring system. This approach enables the transformation of accessible steroids into rare ones, demonstrated by synthesizing 5,6‐dihydro‐ophiopogonol A
Chiara Maioli   +8 more
wiley   +1 more source

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