Results 61 to 70 of about 152,659 (266)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Sustainable Dynamic Wrinkle Efficacy: Non-Invasive Peptides as the Future of Botox Alternatives

open access: yesCosmetics
Dynamic wrinkle reduction continues to challenge aesthetic dermatology, predominantly addressed through Botulinumtoxin (Botox) injections. Despite Botox’s robust efficacy with up to an 80% reduction in wrinkle visibility within just one week, its ...
Trang Thi Minh Nguyen   +7 more
doaj   +1 more source

Huiles, corps gras et produits cosmétiques

open access: yesOléagineux, Corps gras, Lipides, 2004
Cosmetic and fat industries maintain close relationship of customer to supplier. Fats being considered either as excipients or as invaluable active ingredients for the cosmetic industry.
Rancurel Alain
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Review of Aryl Hydrocarbon Receptor–Mediated Immune Regulation in Cutaneous Squamous Cell Carcinoma Progression

open access: yesImmunoTargets and Therapy
Huiyan Han,1 Qinyi Dong,2 Zijian Zhang,2 Siying Li,1 Han Zhang,1 Xinman Wang,1 Jiahao Bai,1 Lei Shi,1 Xiaoyi Fu,2 Kaili Zheng,1 Lili Liang1 1The Cosmetic and Plastic Surgery Department of Shanxi Provincial People’s Hospital, Shanxi Medical University ...
Han H   +10 more
doaj  

Alkenones as a Promising Green Alternative for Waxes in Cosmetics and Personal Care Products

open access: yesCosmetics, 2018
The move toward green, sustainable, natural products has been growing in the cosmetic and personal care industry. Ingredients derived from marine organisms and algae are present in many cosmetic products. In this study, a new green ingredient, a wax (i.e.
Kyle McIntosh   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

High-Dose Baricitinib for Severe Alopecia Areata with Suboptimal Response to Conventional Therapy: A Real-World Assessment

open access: yesClinical, Cosmetic and Investigational Dermatology
Qinsi Liu, Mang Sun, Yuwei Cao, Hengguang Zhao Department of Dermatology & Cosmetic Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of ChinaCorrespondence: Hengguang Zhao ...
Liu Q, Sun M, Cao Y, Zhao H
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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