Results 121 to 130 of about 5,398,504 (301)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Cosmetic surgery in the age of gender

open access: yes, 2009
We're watching a clip from a TV docnmentary about cosmetic surgery on YouTube.' It introduces Toni Wildish, 28-year-old mother of four, part-time shop assistant, and aspiring glamour model.
Jones, MR, Heyes, CJ
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Cosmetic Contact Allergens

open access: yes, 2016
This article presents trends in the frequency of cosmetics as causal factors of allergic contact dermatitis during a 26-year period in 14,911 patients patch-tested between 1990 and 2014, and discusses the cosmetic allergens identified during the last six
An Goossens
core   +1 more source

Comparing Absorbable and Nonabsorbable Sutures in Corporeal Plication for Treatment of Congenital Penile Curvature

open access: yesUrology Journal, 2011
PURPOSE: To compare the outcome of corporeal plication using absorbable versus nonabsorbable sutures for the treatment of congenital penile curvature.MATERIALS AND METHODS: Thirty-eight men older than 15 years old with congenital penile curvature were ...
Abbas Basiri   +3 more
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Current materials and techniques in cosmetic hand injections

open access: yesJournal of Plastic Surgery and Hand Surgery
Background: With the widespread popularity and development of aesthetic treatments, the focus has extended from facial aging to include the aging of hands.
Yutong Liang   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Promosi Melalui Endorse Pada Produk Kosmetik Wardah Ditinjau Dari Perspektif Bisnis Syariah (Studi Kasus Pada Mahasiswa Fakultas Ekonomi dan Bisnis Islam UIN Fatmawati Sukarno Bengkulu)

open access: yesAl-Intaj
This study aims to  determine promotion through endorsement in increasing consumer buying interest in wardah cosmetic products and the application of sharia business principles in the promotion of endorsement on wardah cosmetic products.
Yeka Effrianti, Eka Sri Wahyuni
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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