Results 151 to 160 of about 5,398,504 (301)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Aesthetic techniques for melanocytic nevus management: clinical outcomes, cosmetic satisfaction, and safety-a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Guo Z, Wang C.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Development of a Novel VDR-Activating Peptide as a Functional Cosmetic Ingredient for Skin Barrier Health and Photoprotection

The vitamin D receptor (VDR) plays a pivotal role in maintaining epidermal barrier homeostasis and regulating cutaneous inflammatory responses. However, the cosmetic application of vitamin D and its active metabolites is limited by photoinstability ...
Min-Seo Kim, Jang-Hee Hahn
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Influence of Physical Attractiveness and Cosmetic Aesthetic Plastic Surgery Attitude on Cosmetic Surgery Tour Participation of Females

, 2009
[[abstract]]With the change of economic environment and the upgrade of life quality, more and more people who satisfy with the basic physiological needs, start to pursuit of luxury and high levels of demand about remodeling appearance.
Huang Yu-Ting
core  

Risk-Based Assessment of Cosmetic Preservation Using Raw-Material-Associated Microorganisms in an Adapted EN ISO 11930 Challenge Test

Cosmetic formulations containing natural or minimally processed raw materials are prone to microbial contamination, which can compromise product safety and quality.
Robert Beinio, Dirk P. Bockmühl, Ghazaleh Fazlikhani, Binal Dobariya, Marian E. Delsing   +4 more
core   +1 more source

Triangular Osteotomies for Y-shaped Metacarpal Synostosis. [PDF]

Plast Reconstr Surg Glob Open
Benlier E, Akyar F.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Operational Standard for Tissue-Extracted Collagen Facial Injection Techniques. [PDF]

Clin Cosmet Investig Dermatol
Ao Y, Wang X, Shi B.
europepmc   +1 more source