Results 121 to 130 of about 282,477 (312)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

The pursuit of beauty in ‘the age of powder and paint" [PDF]

, 2017
The British eighteenth century was an age of elegance. A vital importance was put on appearances and the consumer boom of the time assumed epic proportions. Towards the end of the century complexions became increasingly more colourful and hairstyles more
Rodrigues, Patricia
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Anti-Makeup: Learning A Bi-Level Adversarial Network for Makeup-Invariant Face Verification

, 2017
Makeup is widely used to improve facial attractiveness and is well accepted by the public. However, different makeup styles will result in significant facial appearance changes. It remains a challenging problem to match makeup and non-makeup face images.
He, Ran, Li, Yi, Song, Lingxiao, Tan, Tieniu, Wu, Xiang   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Prospective, Randomized, Double‐Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population

Health Science Reports
Background and Aims Asian skin is more sensitive than Caucasian. When it comes to anti‐aging treatments, some classic actives like Retinoids, are not friendly to Asian skin due to irritation issues.
Xuefang Shi, Yimeng Wang, Huihui Zhang, Tao Zhang   +3 more
doaj   +1 more source

Red rice extract as a biological UV filter and its photoprotective enhancement effects

Journal of Dermatologic Science and Cosmetic Technology
Background: Long-term exposure to sunlight can lead to inflammatory responses, skin photoaging and cancers. Plant extracts can serve as effective biological UV (ultraviolet) filters for their UV absorption capacity.
Tao Zhang, Shangqian Ning, Yang-Chi-Dung Lin, Tianyang Li, Xueting Zhao, Hao Liu, Yue Liu, Qing Lv, Ye Gu, Zhihua Zhang, Linge Fan   +10 more
doaj   +1 more source

Breast cysts and aluminium-based antiperspirant salts [PDF]

, 2019
On the basis that aluminium-based antiperspirant salts are designed to block apocrine sweat ducts of the axilla, and that breast cysts result from blocked breast ducts in the adjacent region of the body, it has been proposed that breast cysts may arise ...
Darbre, Philippa
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source