Results 91 to 100 of about 34,734 (271)

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Spaces with a $\mathbb{Q}$-diagonal

, 2018
A space $X$ has a $\mathbb{Q}$-diagonal if $X^2\setminus \Delta$ has a $\mathcal{K}(\mathbb{Q})$-directed compact cover. We show that any compact space with a $\mathbb{Q}$-diagonal is metrizable, hence any Tychonorff space with a $\mathbb{Q}$-diagonal is
Feng, Ziqin
core   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Day-to-Day Variability of the Semidiurnal Tide in the F-Region Ionosphere During the January 2021 SSW From COSMIC-2 and ICON. [PDF]

Geophys Res Lett, 2022
Oberheide J.
europepmc   +1 more source

Study of cosmic rays in the solar environment Final technical report [PDF]

Behavior of cosmic rays in solar environment ...

core   +1 more source

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self‐Assembled Polydiacetylene‐Silk Core‐Shell Vesicles

Advanced Science, EarlyView.
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti, Giulia Guidetti, Elisabetta Ruggeri, Terri Lyne Carrington, Fiorenzo G. Omenetto   +4 more
wiley   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Lyα Emission at z = 7–13: Clear Evolution of Lyα Equivalent Width Indicating a Late Cosmic Reionization History

The Astrophysical Journal
We present the evolution of Ly α emission derived from 53 galaxies at z = 6.6–13.2, which have been identified by multiple JWST/NIRSpec spectroscopy programs of Early Release Science, General Observer, Director's Discretionary Time, and Guaranteed Time ...
Minami Nakane, Masami Ouchi, Kimihiko Nakajima, Yuichi Harikane, Yoshiaki Ono, Hiroya Umeda, Yuki Isobe, Yechi Zhang, Yi Xu   +8 more
doaj   +1 more source

Extensive Air Showers and Cosmic Ray Physics above 1017 eV

EPJ Web of Conferences, 2016
Cosmic Rays above 1017 eV allow studying hadronic interactions at energies that can not be attained at accelerators yet. At the same time hadronic interaction models have to be applied to the cosmic-ray induced air-shower cascades in atmosphere to infer ...
Bertaina Mario
doaj   +1 more source

From interstellar abundances to grain composition: the major dust constituents Mg, Si and Fe

, 2010
We analyse observational correlations for three elements entering into the composition of interstellar silicate and oxide grains. Using current solar abundances (Asplund et al. 2009), we convert the gas-phase abundances into dust-phase abundances for 196
Henning, Th., Voshchinnikov, N. V.
core   +1 more source