Results 71 to 80 of about 17,777,046 (306)

cosmic-popsynth/cosmic: 2.0.0 [PDF]

open access: yes, 2019
<p>cosmic (Compact Object Synthesis and Monte Carlo Investigation Code)</p> <p>cosmic is a rapid binary population synthesis suite with a special purpose of generating realistic compact binary populations.
Coughlin, Scott (5933717)   +11 more
core   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

The 22-Year Hale Cycle in Cosmic Ray Flux – Evidence for Direct Heliospheric Modulation [PDF]

open access: yes, 2014
The ability to predict times of greater galactic cosmic ray (GCR) fluxes is important for reducing the hazards caused by these particles to satellite communications, aviation, or astronauts.
Thomas, SR, Lockwood, M, Owens, MJ
core  

Changes in cloud cover associated with Forbush decreases of galactic cosmic rays [PDF]

open access: yes, 2001
The results of a study to quantify the relationship between cloud cover and short-term Forbush decreases (FD) of galactic cosmic ray flux are presented. Using an extensive record of global satellite-derived cloud products from the International Satellite
Kniveton, DR   +5 more
core   +1 more source

Nonthermal Emissions from a Head–Tail Radio Galaxy in 3D Magnetohydrodynamic Simulations

open access: yesThe Astrophysical Journal, 2023
We present magnetohydrodynamic simulations of a jet–wind interaction in a galaxy cluster and the radio to gamma-ray and neutrino emissions from this “head–tail galaxy.” Our simulation follows the evolution of cosmic-ray (CR) particle spectra with energy ...
Takumi Ohmura   +4 more
doaj   +1 more source

Femtosecond‐Laser Nanocavitation Regenerates SERS‐Active Plasmonic Nanogaps for Longitudinal Molecular Sensing at Biointerfaces

open access: yesAdvanced Science, EarlyView.
A regenerative molecular sensing platform that co‐localizes surface‐enhanced Raman spectroscopy (SERS) sensing and nanocavitation‐based actuation. Femtosecond‐laser triggered nanocavitation produces thermomechanical forces to locally regenerate SERS‐active nanogaps in protein‐rich biofluids while preserving optical performance.
Aditya Garg   +8 more
wiley   +1 more source

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

open access: yesHeliyon, 2020
The pathophysiology of type 2 diabetes mellitus (T2DM) is characterized by not only insulin resistance, but also the abnormal regulation of glucagon secretion, suggesting that antagonizing the glucagon-induced signaling pathway has therapeutic potential ...
Megumi Funakoshi-Tago   +4 more
doaj   +1 more source

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin   +23 more
wiley   +1 more source

Cosmic expansion in homogeneous and inhomogeneous universes : supernovae type Ia as cosmic probes [PDF]

open access: yes, 2010
Seikel M. Cosmic expansion in homogeneous and inhomogeneous universes : supernovae type Ia as cosmic probes. Bielefeld (Germany): Bielefeld University; 2010.Since it has been discovered in the late 1990s that the universe is likely to be expanding ...
Seikel, Marina
core   +1 more source

Time resolution of cosmic noise observations with a correlation experiment [PDF]

open access: yes, 2004
International audienceA radio wave correlation experiment using a Mills Cross technique can be used to observe the cosmic noise intensity from the ground for the purpose of determining the absorption in the ionosphere.
E. Nielsen   +5 more
core   +1 more source

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