Results 91 to 100 of about 35,666 (219)

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

From patient notes to prognostication: The revolutionary potential of event‐based foundation models in orthopaedics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI)‐equipped tools into electronic health record (EHR) platforms may drive the evolution of orthopaedic diagnosis and decision‐making, leveraging big data to generate precise and context‐aware insights.
Alexander M. Bouterse, James A. Pruneski, Felix C. Oettl, Bálint Zsidai, Umile Giuseppe Longo, Thomas Tischer, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

Rapid and quantitative phage susceptibility test by ramanome

mLife, EarlyView.
Abstract Antimicrobial resistance poses an escalating global threat, renewing interest in bacteriophage therapy as a precision alternative to antibiotics. However, clinical translation remains hindered by the lack of rapid and quantitative phage susceptibility testing (PST) platforms capable of evaluating host range, infection potency, and effective ...
Xiao Han, Xiaofu Wan, Yang Zhou, Xiaoting Fu, Xiaoshan Zheng, Bo Gao, Shi Huang, Anle Ge, Jiadong Huang, Hongzhou Lu, Jian Xu   +10 more
wiley   +1 more source

Life in the Bubble: How a Nearby Supernova Left Ephemeral Footprints on the Cosmic-Ray Spectrum and Indelible Imprints on Life

The Astrophysical Journal Letters
The Earth sits inside a 300 pc-wide void that was carved by a series of supernova explosions that went off tens of millions of years ago, pushing away interstellar gas and creating a bubble-like structure.
Caitlyn Nojiri, Noémie Globus, Enrico Ramirez-Ruiz   +2 more
doaj   +1 more source

Do cultural taboos regulate hunting in transitioning Indigenous communities? The case of the Idu Mishmi of Northeast India

People and Nature, EarlyView.
Abstract There is rising recognition of resource‐use rights of Indigenous Peoples and Local Communities (IPLCs) within wildlife conservation. Historically, sociocultural institutions ensured wildlife sustainability in many IPLC areas. However, the future viability of such institutions is uncertain as IPLCs change in response to external pressures and ...
Sahil Nijhawan, Achili Mihu, Iho Tapo, Alinji Rondo, Jibi Pulu, Marcus Rowcliffe   +5 more
wiley   +1 more source

Constraints on the speed of sound in the k-essence model of dark energy

European Physical Journal C: Particles and Fields
We consider a k-essence scalar field model for the late-time cosmic acceleration in which the sound speed, parametrized as $$c_s$$ c s is constant. We compute the relevant background and perturbation quantities corresponding to the observables like ...
Bikash R. Dinda, Narayan Banerjee
doaj   +1 more source

Enabling Variant Proteogenomic Assay Development Through a Peptide Target Selection Pipeline and Web Application

PROTEOMICS, EarlyView.
ABSTRACT The quantification of key protein variants can guide precision oncology to enable better identification of driver mutations. Bottom‐up assays infer parent protein levels through the quantification of surrogate peptides. Assay methods designed for absolute quantification of protein variants, such as multiple reaction monitoring mass ...
Constantinos Blidjios, Pallab Bhowmick, Vincent R. Richard, Yassene Mohammed, Christoph H. Borchers   +4 more
wiley   +1 more source

Multiproxy Chronologies of the Hurd Rock Glacier (Livingston Island, South Shetland Islands, Maritime Antarctica): Between the Late‐Stage Stabilization and Flow Deceleration

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT The Hurd Rock Glacier, located on Livingston Island (South Shetland Islands archipelago, Maritime Antarctica), is a tongue‐shaped feature composed of angular boulders, displaying transverse ridges and furrows, and featuring lobate structures, which are more prominently developed in its frontal sector.
Rosana Menéndez‐Duarte, Jesús Ruiz‐Fernández, Laura Rodríguez‐Rodríguez, José M. Fernández‐Fernández, Vincent Rinterknecht, ASTER Team   +5 more
wiley   +1 more source

The Evolution of Autonomous Systems for Planetary Cave Exploration: A Review

Journal of Field Robotics, EarlyView.
ABSTRACT The exploration of Subsurface Access Points (SAPs), such as lava tubes on the Moon and Mars, has gained significant interest due to their potential as stable environments shielded from surface radiation and temperature extremes. These sites are considered high‐value targets for detecting water and signs of ancient life, and assessing their ...
Sarah Swinton, Daniel Mitchell, Jamie Blanche, Euan McGookin, David Flynn   +4 more
wiley   +1 more source

From Flybys to Sample Return: A Review of Space Probes and Robotic Sampling Technologies for Small Bodies

Journal of Field Robotics, EarlyView.
ABSTRACT As a crucial puzzle piece of deep space exploration, exploring small bodies can provide significant scientific insights and valuable mineral resources. Unlike missions to the Moon and Mars, small‐body missions pose distinct technical challenges, including communication delays, weak gravity, and uncertain environments. This paper reviews a full
Xin Zhang, Hao Zhou, Dalin Zhou, Zhaojie Ju   +3 more
wiley   +1 more source