Results 61 to 70 of about 17,777,046 (306)
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
Advanced Science, EarlyView.This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
Dedicated Cosmic Ray Measurements for Space Weather and Educational Purposes [PDF]
, 2014 This paper describes the Global Muon Detector Network (GMDN) data applied to Tohuku earthquake and Fukushima nuclear power plant failure. In addition the DLR_School_Lab is introduced by the display of Coronal Mass Ejections due to GMDN data and by ...
Winkler, Partick +13 more
core +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
Advanced Science, EarlyView.ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics
Advanced Science, EarlyView.stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang +3 more
wiley +1 more source
Advanced Science, EarlyView.STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li +9 more
wiley +1 more source
Cosmic strings and scalar tensor gravity [PDF]
, 1999 This thesis is concerned with the study of cosmic strings. We studied the values for the Higgs mass and string coupling for which the gravitational effect of an infinite cosmic string in the context of the Einstein theory is not only locally but also ...
Da Silva, Caroline Dos Santos +1 more
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Comparative Study of the Dynamics of Cosmic Rays for the Pakistan and China Atmospheric Regions
Journal of Mathematical and Fundamental Sciences, 2020 This paper presents an analysis of cosmic ray intensity in Pakistan air space using spatial interpolation, comparing it with Chinese cosmic ray records from 1984 to 1993.
Faisal Nawaz +4 more
doaj +1 more source
Cosmic Union of Communities: a New Concept and Technologies of Creating Cosmic Humanity [PDF]
Философия и космология, 2019 The article deals with the philosophical foundations of the theory and practice of creating Cosmic Humanity. It suggests a new idea, concept and technology of organizing cosmic communities, i.e.
Sergey Krichevsky
doaj +1 more source
Advanced Science, EarlyView.Two‐dimensional CuInP2S6 nanosheets are incorporated into a P(VDF‐TrFE) matrix to induce polarization‐cooperative ferroelectric coupling. The resulting P(VDF‐TrFE)/CuInP2S6 hybrid film exhibits reinforced ferroelectric ordering and reduced coercive electric fields compared with pristine P(VDF‐TrFE).
Yeonsu Jeong +10 more
wiley +1 more source
, 2008 The cosmic radiation incident at the top of the terrestrial atmosphere includes all stable charged particles and nuclei with lifetimes of order 106 years or longer.
Cosmic Rays
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