Results 61 to 70 of about 91,143 (269)

Femtosecond‐Laser Nanocavitation Regenerates SERS‐Active Plasmonic Nanogaps for Longitudinal Molecular Sensing at Biointerfaces

Advanced Science, EarlyView.
A regenerative molecular sensing platform that co‐localizes surface‐enhanced Raman spectroscopy (SERS) sensing and nanocavitation‐based actuation. Femtosecond‐laser triggered nanocavitation produces thermomechanical forces to locally regenerate SERS‐active nanogaps in protein‐rich biofluids while preserving optical performance.
Aditya Garg, Ze Zong, Meitong Nie, Stacie E. Deaver, Elizabeth M. Van Order, Elieser Mejia, Peter Vikesland, Erin S. Gloag, Wei Zhou   +8 more
wiley   +1 more source

From Flow to Function: Using Different Static Mixers to Fabricate Microarchitected Materials Via Chaotic Printing

Advanced Science, EarlyView.
Complex microarchitectures emerge from simple flow‐driven transformations as static mixers iteratively reorient and split material domains. Coupled with diverse deposition strategies, chaotic printing provides an accessible platform for fabricating architected materials that support biologically and chemically relevant processes. ABSTRACT Nature builds
Edna Johana Bolívar‐Monsalve, Carlos Fernando Ceballos‐González, Diego Alonso Quevedo‐Moreno, Irving Isaí Rendón‐Moreno, Ariel Cantoral‐Sánchez, Héctor Ambriz‐González, Mario Moisés Alvarez, Grissel Trujillo‐de Santiago   +7 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

The STELLA Robotic Observatory on Tenerife

Advances in Astronomy, 2010
The Astrophysical Institute Potsdam (AIP) and the Instituto de Astrofísica de Canarias (IAC) inaugurated the robotic telescopes STELLA-I and STELLA-II (STELLar Activity) on Tenerife on May 18, 2006.
Klaus G. Strassmeier, Thomas Granzer, Michael Weber, Manfred Woche, Emil Popow, Arto Järvinen, Janos Bartus, Svend-Marian Bauer, Frank Dionies, Thomas Fechner, Wilbert Bittner, Jens Paschke   +11 more
doaj   +1 more source

Three-dimensional earthward fast flow in the near-Earth plasma sheet in a sheared field: comparisons between simulations and observations [PDF]

Annales Geophysicae, 2009
Three-dimensional configuration of earthward fast flow in the near-Earth plasma sheet is studied using three-dimensional magnetohydrodynamics (MHD) simulations on the basis of the spontaneous fast reconnection model.
K. Kondoh, M. Ugai
doaj   +1 more source

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

Advanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng, Jingyu Chen, Lang Xia, Tao Wang, Yuzhou Wang, Lei Zhang, Guofang Zhao, Long Xu, Juemin Yu, Yunlang She, Junqi Wu, Yue Zhao, Chang Chen, Deping Zhao   +13 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Extreme outflow velocities and weak UV emission lines indicate quasars shedding their dust cocoons

Astronomy & Astrophysics
The recently discovered low-ionisation broad absorption line (LoBAL) quasar GQ 1309+2904 is unusual due to its very broad, highly blueshifted absorption troughs and an absence of broad emission lines except for Hα.
Ma Guozhen, Geier Stefan J., Fynbo Johan P. U., Christensen Lise, Berdyugin Andrei, Frederiksen Rasmus, Heintz Kasper E., Henriksen Phillip D., Krogager Jens-Kristian, Ledoux Cédric, Piirola Vilppu, Møller Palle, Vejlgaard Simone, Choi Hyunseop   +13 more
doaj   +1 more source

Integrated geophysical‐petrological modeling of lithosphere‐asthenosphere boundary in central Tibet using electromagnetic and seismic data

Geochemistry, Geophysics, Geosystems, 2014
We undertake a petrologically driven approach to jointly model magnetotelluric (MT) and seismic surface wave dispersion (SW) data from central Tibet, constrained by topographic height. The approach derives realistic temperature and pressure distributions
Jan Vozar, Alan G. Jones, Javier Fullea, Matthew R. Agius, Sergei Lebedev, Florian Le Pape, Wenbo Wei   +6 more
doaj   +1 more source