Results 151 to 160 of about 186,949 (193)

Abstract 4319: The need for new publication standards in cancer genomics, lessons from curating COSMIC database

open access: closedCancer Research, 2023
A consequence of the progress in cancer genomics is the exponential growth in data produced by research and clinical projects. Given the limited capacity within a scientific manuscript to share experimental data, various approaches have been developed:
Alexander Holmes   +2 more
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Abstract 4312: Identification of shared mutations across many parallel human and canine cancers based on comprehensive survey of canine cancer mutations and the “caninization” of human mutations from COSMIC

Cancer Research, 2023
Introduction: Vidium Insight™ is a canine cancer genomic biomarker database built from exhaustive curation of peer-reviewed literature describing genomic mutations in canine cancers.
Sharadha Sakthikumar   +5 more
semanticscholar   +1 more source

Abstract 5028: Integration of molecular data into cancer patient database

Cancer Research, 2022
Background: Precision medicine holds promise of being a more effective method for treating complex diseases such as cancer. Nuanced care is needed, as the development and clinical course of cancer is multifactorial with influences from the general ...
Basil H. Chaballout   +8 more
semanticscholar   +1 more source

Abstract 906: COSMIC: Describing the world’s knowledge of somatic mutations in cancer

Bioinformatics, Convergence Science, and Systems Biology, 2019
COSMIC, the Catalogue Of Somatic Mutations In Cancer (http://cancer.sanger.ac.uk/cosmic) is a continual effort to integrate all available information on somatic mutations and other molecular alterations causing every form of human cancer. Being the world’
S. Forbes   +23 more
semanticscholar   +1 more source

Abstract 3143: A bioinformatic pipeline for identifying change-of-metabolic-function cancer mutations

Cancer Research, 2023
Cancer arises through clonal evolution, in some cases selecting change of metabolic function (COMF) mutations that functionally alter proteins to affect cellular metabolism.
Kevin J. Tu   +5 more
semanticscholar   +1 more source

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