Results 151 to 160 of about 277,677 (243)

Genome-wide somatic mutation analysis of sinonasal adenocarcinoma with and without wood dust exposure

open access: yesGenes and Environment
Background Sinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the non-intestinal-type sinonasal adenocarcinoma (non-ITAC). Occurrence of ITAC is strongly associated with
Lauri J. Sipilä   +10 more
doaj   +1 more source

CAMIRADA: Cancer microRNA association discovery algorithm, a case study on breast cancer [PDF]

open access: yesarXiv, 2018
In recent studies, non-coding protein RNAs have been identified as microRNA that can be used as biomarkers for early diagnosis and treatment of cancer, that decrease mortality in cancer. A microRNA may target hundreds or thousands of genes and a gene may regulate several microRNAs, so determining which microRNA is associated with which cancer is a big ...
arxiv  

Relationship of fat in the pancreas with cardiovascular disease: A systematic review and meta‐analysis

open access: yesObesity Reviews, EarlyView.
Summary Background General adiposity is a well‐known risk factor for cardiovascular disease. By contrast, the interconnection between high intra‐pancreatic fat deposition and cardiovascular disease has been scantily investigated. This field‐wide systematic review aimed to map the available evidence on cardiovascular disease according to the fat content
Yingxin Zhang   +2 more
wiley   +1 more source

CAMIRADA: Cancer microRNA association discovery algorithm, a case study on breast cancer [PDF]

open access: yesarXiv, 2019
In recent studies, non-coding protein RNAs have been identified as microRNA that can be used as biomarkers for early diagnosis and treatment of cancer, that decrease mortality in cancer. A microRNA may target hundreds or thousands of genes and a gene may regulate several microRNAs, so determining which microRNA is associated with which cancer is a big ...
arxiv  

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

Superluminous supernovae: No threat from Eta Carinae

open access: yes, 2007
Recently Supernova 2006gy was noted as the most luminous ever recorded, with a total radiated energy of ~10^44 Joules. It was proposed that the progenitor may have been a massive evolved star similar to eta Carinae, which resides in our own galaxy at a ...
Adrian L. Melott   +5 more
core   +1 more source

Diagnostic and prognostic genomic aberrations in upper tract urothelial carcinoma can be identified in focal barbotage samples

open access: yesBJU International, Volume 135, Issue 5, Page 792-801, May 2025.
Objectives To investigate whether genetic analysis of focal barbotage samples obtained at ureterorenoscopy (URS) is possible, and to identify genetic aberrations that might add prognostic information. Methods This prospective study included barbotage samples from 42 patients with upper urinary tract urothelial carcinoma (UTUC) confirmed at URS. At URS,
Tomas Andri Axelsson   +8 more
wiley   +1 more source

Septin mutations in human cancers

open access: yesFrontiers in Cell and Developmental Biology, 2016
Septins are GTP-binding proteins that are evolutionarily and structurally related to the RAS oncogenes. Septin expression levels are altered in many cancers and new advances point to how abnormal septin expression may contribute to the progression of ...
Elias T Spiliotis, Dimitrios Angelis
doaj   +1 more source

Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution. [PDF]

open access: yes, 2020
The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in Drosophila, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals ...
Chen, Yuxuan   +7 more
core  

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