Results 101 to 110 of about 14,844 (293)

Efforts to Prevent the Neglect of Traditional Indigenous Medicine: Policy Insights From Bolivia

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Traditional Indigenous medicine has existed for centuries, but only recently has it obtained international recognition. Some countries have been working on the integration of traditional Indigenous healing practices in their national health systems.
Carlos Rosas‐Jiménez, Roberto Tola, Melina Flores, Sonia Cruz, Gonzalo Huanca, Cynthia Lokker, Bonny Ibhawoh, Lisa Schwartz   +7 more
wiley   +1 more source

CLASSY. IX. The Chemical Evolution of the Ne, S, Cl, and Ar Elements

The Astrophysical Journal
To study the chemical evolution across cosmic epochs, we investigate Ne, S, Cl, and Ar abundance patterns in the Cosmic Origins Spectrograph Legacy Archive Spectroscopic SurveY (CLASSY). CLASSY comprises local star-forming galaxies (SFGs; 0.02 < z < 0.18)
Karla Z. Arellano-Córdova, Danielle A. Berg, Matilde Mingozzi, Bethan L. James, Noah S. J. Rogers, Evan D. Skillman, Fergus Cullen, Ryan K. Alexander, Ricardo O. Amorín, John Chisholm, Matthew Hayes, Timothy Heckman, Svea Hernandez, Nimisha Kumari, Claus Leitherer, Crystal L. Martin, Michael Maseda, Themiya Nanayakkara, Kaelee Parker, Swara Ravindranath, Allison L. Strom, Fiorenzo Vincenzo, Aida Wofford   +22 more
doaj   +1 more source

Materials and Music: Selective Imperfection as a Generative Framework for Analysis, Creativity and Discovery

Interdisciplinary Materials, EarlyView.
Vibrations in matter, from spider webs to molecules, water to flames, share a grammar with music. We propose that creativity emerges when constraints force expansion beyond existing possibilities. Selective imperfection restores balance, enabling invention.
Markus J. Buehler
wiley   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

The Steep-spectrum Radio-loud Active Galactic Nucleus Luminosity Function and Its Implications for Black Hole Growth and Star Formation

The Astrophysical Journal Supplement Series
We study the cosmic evolution of radio-loud active galactic nuclei (AGNs) using a beaming-minimized sample of 4555 steep-spectrum sources compiled from the XXL survey, VLA-COSMOS, and other wide-field datasets.
Wenjie Wang, Zunli Yuan, Bruno Šlaus, Hongwei Yu, Yu Luo   +4 more
doaj   +1 more source