Results 101 to 110 of about 12,121 (264)

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

More scalings from cosmic strings

Journal of High Energy Physics
We analyze all individual cosmic strings of various lengths in a large ensemble of the global cosmic string networks in the post-inflationary scenario, obtained from numerical simulations on a discrete lattice with N 3 = 40963.
Heejoo Kim, Minho Son
doaj   +1 more source

Putative trait‐based retention of oral‐derived microbes along the oral–gut axis in bamboo‐eating pandas

iMetaOmics, EarlyView.
Compared with the two herbivorous comparison species, pandas showed higher estimated oral‐source contributions and enrichment of microbial traits associated with facultative anaerobiosis, biofilm formation, and stress tolerance. These patterns are consistent with a model in which greater oral microbial input and putative host filtering may jointly ...
Lu Huang, Xiaoci Fan, Xinyue Tian, Yiying Wu, Yue Liu, Wei Wei, Honglin Wu, Lifeng Zhu   +7 more
wiley   +1 more source

Evolution of Cosmic System [PDF]

, 2012
What does it mean that the cosmic radio wave flux density varies with the passage of time is an interesting question; the radio wave is of the quasar, a system of galaxy, which is distributed in our universe from a few billions of light years to the distanse close to the big bang age and has been radiating immense electromagnetic energy from it by the ...
openaire   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Matter creation in unimodular gravity cosmology

Physics Letters B
We investigate matter creation in the cosmological framework of unimodular gravity. We keep the energy density ρ , pressure p , particle number density n , and particle number N = n V as the physical thermodynamic variables of the matter sector, and ...
Víctor H. Cárdenas, Miguel Cruz, Samuel Lepe   +2 more
doaj   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

Translating Riedl: The Circulation and Operationalisation of Evolutionary Ideas

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Rupert Riedl's Order in Living Organisms proposed a systems theory of evolution decades before the concepts it pioneered—homology, burden, the imitative epigenotype—reached the agenda of evolutionary biology. This paper reconstructs the lineages that operationalized his insights across several fields and explores the internal and external reasons for ...
Laura Nuño de la Rosa
wiley   +1 more source

COSMIC: A Galaxy Cluster–Finding Algorithm Using Machine Learning

The Astrophysical Journal Supplement Series
Building a comprehensive catalog of galaxy clusters is a fundamental task for studies on structure formation and galaxy evolution. In this paper, we present Cluster Optical Search using Machine Intelligence in Catalogs (COSMIC), an algorithm utilizing ...
Da-Chuan Tian, Yang Yang, Zhong-Lue Wen, Jun-Qing Xia   +3 more
doaj   +1 more source