Results 201 to 210 of about 14,844 (293)

Elucidating PI3K/AKT/PTEN Pathway Alterations at Single‐Cell Level in CTCs From HR+/HER2− Metastatic Breast Cancer

Cancer Science, EarlyView.
Single CTC analysis revealed extensive inter‐ and intra‐patient heterogeneity of PI3K/AKT/PTEN pathway alterations in HR+/HER2− metastatic breast cancer, capturing both SNVs and CNAs, including PTEN loss‐of‐function events. Longitudinal CTC profiling also uncovered dynamic clonal evolution, highlighting its potential to complement tissue and ctDNA ...
Tania Rossi, Michela Palleschi, Caterina Gianni, Filippo Merloni, Alessandra Virga, Sara Bandini, Davide Angeli, Michela Tebaldi, Roberta Maltoni, Paola Ulivi, Antonino Musolino   +10 more
wiley   +1 more source

Radiation-Resistant Microbes: Pioneers for Life Beyond Earth. [PDF]

Curr Microbiol
Coleine C, Cordero RJ.
europepmc   +1 more source

Scalable Computation of Topological Abstractions for Scalar Data

Computer Graphics Forum, EarlyView.
Abstract Topological data analysis has become an important tool for large scale scalar data analysis and visualization, efficiently extracting the inherent structure and features of interest of the data. However, with growing dataset sizes and complexity, it is increasingly becoming infeasible to compute topological abstractions of interest in serial ...
M. Will, J. Lukasczyk, J. Tierny, A. Gyulassy, G. H. Weber, H. Carr, C. Garth   +6 more
wiley   +1 more source

Metastatic progression of pheochromocytoma and paraganglioma occurs via parallel evolution. [PDF]

NPJ Precis Oncol
Pregnall AM, Wubbenhorst B, D'Andrea K, Pluta J, Amjad W, Shilan J, Cohen DL, Weathers B, Bennett B, Bonanni M, Montone K, Nathanson KL, Wachtel H.   +12 more
europepmc   +1 more source

Survey on Compositional 3D Indoor Scene Generation

Computer Graphics Forum, EarlyView.
This survey provides a comprehensive overview of compositional 3D indoor scene generation, introducing a unified framework for categorizing existing methods, comparing their strengths and limitations and identifying key challenges and future research directions.
H. I. I. Tam, H. I. D. Pun, A. T. Wang, X. Sun, Q. Wu, H. Lee, A. X. Chang, M. Savva   +7 more
wiley   +1 more source

Circulating cell-free DNA profiling reveals ancestry-dependent genetic variation in metastatic prostate cancer. [PDF]

Mol Biomed
Maleknia S, Hassoun R, Adra N, Shahbazi R.   +3 more
europepmc   +1 more source

Cristiano of Arabia: Did Ronaldo increase Saudi Pro League attendances?

Contemporary Economic Policy, Volume 43, Issue 2, Page 260-270, April 2025.
Abstract In December 2022, Cristiano Ronaldo, five‐time Ballon d’Or winner and the most‐followed person on Instagram, signed for Al‐Nassr in the Kingdom of Saudi Arabia. This marked one of several expensive, recent interventions by the kingdom in global sports markets. We exploit the timing of this event to estimate superstar effects.
Dominik Schreyer, Carl Singleton
wiley   +1 more source

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Paper VIII: Thermodynamic Evolution, Transit Nucleosynthesis, and Cosmic Distillation in the "Blooming Flower" Manifold

Ibrahim Mohammed Mussa
openalex   +2 more sources

Clonal evolution and mutational trajectories of metastatic colorectal cancer shaped by anticancer therapies. [PDF]

Nat Commun
Lee WH, Kim B, Nam CH, Yeo HY, Lee DW, Park SC, Oh JH, Han SS, Lim MC, Kim H, Ju YS, Chang HJ, Cha Y.   +12 more
europepmc   +1 more source