Results 191 to 200 of about 14,844 (293)

ABSTRACTS

open access: yes
Precision Radiation Oncology, EarlyView.
wiley   +1 more source

AlpIce‐1: a database of geochronological and geomorphological constraints on Alps‐wide palaeoglacier fluctuations between the Last Glacial Maximum and the Holocene

open access: yesBoreas, EarlyView.
The AlpIce‐1 database is the first compilation of published geomorphological and geochronological markers constraining build‐up, culmination and decay of glaciers from the Last Glacial Maximum through the Holocene across the entire European Alps. AlpIce‐1 integrates more than 4200 surface‐exposure and radiocarbon ages, homogenized, quality controlled ...
Sarah Kamleitner   +6 more
wiley   +1 more source

Shared cloud interactions unveil a candidate binary-system supernova pair with no known analogue. [PDF]

open access: yesNat Commun
Michailidis M   +5 more
europepmc   +1 more source

Genetic Evolution in BRCA1‐Associated Breast Cancer Reveals Early Driver Mutations Shaping Tumor Features and Prognosis

open access: yesCancer Science, EarlyView.
Multi‐region sequencing of 57 BRCA1‐associated breast cancers identified TP53 as the dominant initial driver, defining a triple‐negative subgroup with biallelic BRCA1 loss and elevated genomic instability. TP53 truncating mutations were enriched in BRCA1 carriers and linked to reduced HRD, EMT activation, and a trend toward worse survival.
Li Hu   +13 more
wiley   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

open access: yesCancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal   +16 more
wiley   +1 more source

The quintom theory of dark energy after DESI DR2. [PDF]

open access: yesNatl Sci Rev
Cai Y, Ren X, Qiu T, Li M, Zhang X.
europepmc   +1 more source

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