Results 41 to 50 of about 242,669 (295)

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Nonlinear Evolution of Cosmic Magnetic Fields and Cosmic Microwave Background Anisotropies [PDF]

, 2005
In this work we investigate the effects of the primordial magnetic fields on cosmic microwave background anisotropies (CMB). Based on cosmological magnetohydrodynamic (MHD) simulations we calculate the CMB anisotropy spectra and polarization induced by ...
G. T. Zatsepin, H. Kodama, Hiroyuki Tashiro, Naoshi Sugiyama, R. M. Athreya, Robi Banerjee, Y. B. Zeldovich   +6 more
core   +2 more sources

Evolution of cosmic strings [PDF]

Physical Review D, 1986
The evolution of a system of cosmic strings is studied using an extended version of an analytic formalism introduced by Kibble. It is shown that, in a radiation-dominated universe, the fate of the string system depends sensitively on the fate of the closed loops that are produced by the interactions of very long strings.
openaire   +2 more sources

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source

HUMANITY IN NATURE: CONSERVING YET CREATING

Zygon, 1989
. Developing a scientifically grounded philosophy of cosmic evolution, and using the moral norm of completeness as dynamic harmony, this paper argues that humans are a part of nature in both its conserving and emergent aspects.
doaj   +2 more sources

Cyclotron emission effect on CMB spectral distortions

, 2006
We investigated the role of the cyclotron emission (CE) associated to cosmic magnetic fields (MF) on the evolution of cosmic microwave background (CMB) spectral distortions.
Burigana, Carlo, Zizzo, Andrea
core   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Investigations of the degree of asymmetry across the dayside magnetopause under southward interplanetary magnetic field using GEOTAIL observations

Earth, Planets and Space
The magnetic reconnection environment around the dayside geomagnetopause under long-lasting southward interplanetary magnetic field (IMF) conditions is investigated using the in-situ observation by GEOTAIL satellite from 1994 to 2019.
Koji Kondoh, Shin-ya Nitta
doaj   +1 more source

Modified gravity with an exponential function of curvature

European Physical Journal C: Particles and Fields, 2020
The role of an exponential function of the scalar curvature in the modified gravity is analyzed. Two models are proposed. A toy model that complies with local and cosmological constraints and gives appropriate qualitative description of the cosmic ...
L. N. Granda
doaj   +1 more source