Results 41 to 50 of about 1,077,211 (296)

Testing the Social Bubble Hypothesis on the Early Dynamics of a Scientific Project: The FET Flagship Candidate FuturICT (2010–2013)

open access: yesEntropy, 2021
We present an analysis of a large emerging scientific project in the light provided by the social bubbles hypothesis (SBH) that we have introduced in earlier papers.
Monika Gisler, Didier Sornette
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Happiness Approach to Cost-Benefit Analysis [PDF]

open access: yes, 2013
Subjective well-being (SWB) surveys ask respondents to quantify their overall or momentary happiness or life-satisfaction, or pose similar questions about other aspects of respondents\u27 mental states.
Foglia, Andrew T., Jennings, Andrew K.
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Optimizing Costs to Collect Local Infauna through Grabs: Effect of Sampling Size and Replication

open access: yesDiversity, 2020
Most ecological studies require a cost-effective collection of multi-species samples. A literature review unravelled that (1) large-sized grabs to collect infauna have been used at greater depths, despite no consistent relationship between grab size and ...
Lidia N. Álvarez   +4 more
doaj   +1 more source

Milton Keynes: an outline cost-benefit study [PDF]

open access: yes, 1968
This is a preliminary survey of some of the factors which would need to be investigated in the design and cost-benefit analysis of alternative transport systems for Milton Keynes.
Lennox, S. G., Tidbury, Joan
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Meta-synthesis analysis of costs and benefits in general and Higher education [PDF]

open access: yesPizhūhish/hā-yi rahbarī va mudīriyyat-i āmūzishī, 2018
Education systems (public and higher) play a key role in the comprehensive development of diverse ecosystems, but in recent decades, with increasing turbulence and global financial crises, governments have lacked funding to provide education.
ahmad keykha
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Benefit and Cost Analysis of Resource Sharing

open access: yesInternational Journal of Librarianship
Libraries are not exempt from rising costs. The situation presented is how libraries can continue to provide services while also finding efficiencies in labor and operational expenditures.
Cherie Weible, Janelle Sander
doaj   +1 more source

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