Results 111 to 120 of about 3,250,553 (364)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

RAY, Anandarup, Cost - Benefit Analysis: Isseus and Methodologies

Estudios Económicos, 1986
RAY, Anandarup, Cost - Benefit Analysis: Isseus and ...
J. E. Cincuenegui
doaj   +2 more sources

Estimation of Social Benefits in Cost-benefit Analysis

Theory, Methodology, Practice, 2012
While examining the cost-benefit analysis related to public policy decisions in the Hungarian and international literature, this paper is looking for the answer to the question of what the methodological principles are according to which the benefit ...
Beáta Fodor
doaj  

Possible Value Analysis based on Symbolic Lattice [PDF]

arXiv
We propose a new static program analysis called program behavior analysis. The analysis aims to calculate possible symbolic expressions for every variable at each program point. We design a new lattice, transfer function, and widening operator to accommodate the analysis. Furthermore, we extend the analysis to interprocedural.
arxiv  

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

A comparative analysis of deep learning architectures with data augmentation and multichannel input for locoregional breast cancer radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Studies on deep learning dose prediction increasingly focus on 3D models with multiple input channels and data augmentation, which increases the training time and thus also the environmental burden and hampers the ease of re‐training. Here we compare 2D and 3D U‐Net models with clinical accepted plans to evaluate the appropriateness of
Rosalie Klarenberg, Nienke L. M. Bakx, Coen W. Hurkmans   +2 more
wiley   +1 more source

Quantification and dosimetric impact of intra‐fractional bladder changes during CBCT‐guided online adaptive radiotherapy for pelvic cancer treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study quantitatively evaluates bladder changes and their dosimetric impact during the on‐couch adaptive process on a commercial CBCT‐based online adaptive radiotherapy (CT‐gART) platform. Methods Data from 183 fractions of ten patients receiving online ART for pelvic cancers were analyzed retrospectively.
Ingrid Valencia Lozano, Elizabeth Buss, Catherine S. Spina, David P. Horowitz, Lisa A. Kachnic, Michael Price, Yi‐Fang Wang, Reshma Munbodh   +7 more
wiley   +1 more source

Conceptual Design and Parametric Optimization of a New Multileveled Horsetail Structure for Bicycle Helmets

Advanced Engineering Materials, EarlyView., 2023
This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng, Dong Ruan, Shanqing Xu, Kwong Ming Tse   +3 more
wiley   +1 more source

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee, Subha Perni, Kelly J. Perrin, Kevin E. Casey, Alexandra O. Leone, Callistus M. Nguyen, Laurence E. Court, He Wang, Xin Wang, Eun Young Han   +9 more
wiley   +1 more source