Emergence of hierarchy in cost driven growth of spatial networks
, 2013 One of the most important features of spatial networks such as transportation networks, power grids, Internet, neural networks, is the existence of a cost associated with the length of links.
Barthelemy, Marc +2 more
core +1 more source
The consequences of implementing non-invasive prenatal testing with cell-free foetal DNA for the detection of Down syndrome in the Spanish National Health Service: a cost-effectiveness analysis [PDF]
, 2019 Juan Carlos Bayón +3 more
openalex +1 more source
Screening strategy to advance HCV elimination in Italy: a cost-consequence analysis
The European Journal of Health EconomicsItaly has the greatest burden of hepatitis C virus (HCV) infection in Western Europe. The screening strategy represents a crucial prevention tool to achieve HCV elimination in Italy. We evaluated the cost-consequences of different screening strategies for the diagnosis of HCV active infection in the birth cohort 1948-1968 to achieve the HCV elimination
Marcellusi A +3 more
openaire +3 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Journal of Marine Science and EngineeringIn the early stages of developing wave energy converter (WEC) projects, a quantitative assessment of component failure consequence costs is essential. The WEC types, deployment site features, and accessibility should all be carefully considered.
Mitra Kamidelivand +7 more
doaj +1 more source
Economic Burden of Type 2 Diabetes Mellitus Treatment Strategies: A Cost Consequence Analysis of Sitagliptin vs Sulfonylureas in Lombardy Region [PDF]
, 2015 Stefano Genovese +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
A digital diagnostic pathway for heart failure: an economic evaluation
Cost Effectiveness and Resource AllocationGuidelines recommend prompt diagnosis of suspected heart failure in people with elevated N-terminal pro b-type natriuretic peptide (NT-proBNP). Early diagnosis of heart failure improves patient outcomes, however diagnosis is complex and can often be ...
Nicola Mcmeekin +8 more
doaj +1 more source
Evaluating the Financial Position and Performance of a typical Dairy Farm in Bulgaria [PDF]
The aim of this paper is to explore the potentials of typical middle sized dairy farms (with 22 cows) to absorb the quotas and market shares released by the small scale farms after the EU accession in 2007.
Vassilev, Zlatan
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source