Results 61 to 70 of about 29,557,581 (269)

Cost–consequence analysis of a hemostatic matrix alone or in combination for spine surgery patients

open access: yes, 2018
Background: A five-year retrospective database analysis comparing the use of Floseal1 flowable topical hemostat alone (F) and in combination with gelatin/thrombin (F + G/T) to achieve hemostasis and control surgical bleeding showed higher resource ...
Manuel G. Ramirez (5637071)   +3 more
core   +1 more source

The death of cost-minimization analysis? [PDF]

open access: yes, 2001
Four different types of evaluation methods, cost-benefit analysis (CBA), cost-utility analysis (CUA), cost-effectiveness analysis (CEA) and cost-minimization analysis (CMA), are usually distinguished. In this note, we pronounce the (near) death of CMA by
Bernie J. O'Brien   +3 more
core   +1 more source

Cost-Consequences of Ultrafiltration for Acute Heart Failure [PDF]

open access: yesCirculation: Cardiovascular Quality and Outcomes, 2009
Background— Ultrafiltration for heart failure may reduce costs associated with acute heart failure by decreasing rehospitalization rates compared to intravenous diuretics. Methods and Results— We developed a decision-analytic ...
Steven M, Bradley   +2 more
openaire   +2 more sources

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Scenario analysis: Results of the cost-consequence analysis from the NHS and hospital perspectives (time horizon: 7 years).

open access: yes, 2019
Scenario analysis: Results of the cost-consequence analysis from the NHS and hospital perspectives (time horizon: 7 years).
Gianluca Furneri (668643)   +3 more
core   +1 more source

Cost-quality tradeoff analysis.

open access: yes, 2023
Cost-quality tradeoff analysis.
Xuemei Li (232384)   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Cost-effectiveness analysis results.

open access: yes, 2022
Cost-effectiveness analysis results.
Mihaela Nica (3357893)   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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