Results 51 to 60 of about 1,281,552 (342)

Costs and savings associated with a pharmacists prescribing for minor ailments program in Saskatchewan

Cost Effectiveness and Resource Allocation, 2017
Background Health care systems around the world have started to develop pharmacists prescribing for minor ailments (PPMA) programs. These programs aim to improve the efficiency of care, reduce physician visits, and increase the accessibility to ...
Ellen Rafferty, Mohsen Yaghoubi, Jeff Taylor, Marwa Farag   +3 more
doaj   +1 more source

WHO key access antibiotics price, availability and affordability in private sector pharmacies in Pakistan

Cost Effectiveness and Resource Allocation, 2021
Background Poor availability and unaffordability of key access antibiotics may increase antimicrobial resistance in the community by promoting inappropriate antibiotic selection and abridged therapy compliance. Objective To check the prices, availability,
Zikria Saleem, Hamid Saeed, Zunaira Akbar, Amna Saeed, Saleha Khalid, Laiba Farrukh, Aleena Irfan, Azka Anam, Mohamed Azmi Hassali, Huma Rasheed, Zaheer-Ud-Din Babar   +10 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Panel discussion on the application of MCDA tools

Cost Effectiveness and Resource Allocation, 2018
Prioritization in healthcare is particularly sensitive to subjective biases and data asymmetry. Yet making data-based and objective decisions are critical to optimizing long term individual and societal benefit.
Michael Watson
doaj   +1 more source

Evaluation of an Alternative Learning System for youths at risk of involvement in urban violence in the Philippines

Cost Effectiveness and Resource Allocation, 2021
Background Globally, violence disproportionately affects young people, leading to injury, hospitalisation, death, social dysfunction, and poor mental wellbeing.
Nishant Mehra, Shr-Jie Sharlenna Wang, Juancho Reyes, Mette Møhl Ambjørnsen, Johan Jarl   +4 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Cost-effectiveness of counseling and pedometer use to increase physical activity in the Netherlands: a modeling study

Cost Effectiveness and Resource Allocation, 2012
Background Counseling in combination with pedometer use has proven to be effective in increasing physical activity and improving health outcomes. We investigated the cost-effectiveness of this intervention targeted at one million insufficiently active ...
Over Eelco AB, Wendel-Vos GC, van den Berg Matthijs, Reenen Heleen H, Tariq Luqman, Hoogenveen Rudolf T, van Baal Pieter HM   +6 more
doaj   +1 more source

Using cost effectiveness analysis; a beginners guide [PDF]

, 2006
Objective ‐ This report seeks to describe the key elements of cost effectiveness analysis (CEA) and to demonstrate how such analysis may be used in the library environment. Methods ‐ The paper uses a step‐by‐step approach to walk the non‐economist
Hulme, C.
core   +1 more source

Cost-effectiveness of physical fitness training for stroke survivors [PDF]

, 2018
Background Physical fitness is impaired after stroke, yet fitness training after stroke reduces disability. Several international guidelines recommend that fitness training be incorporated as part of stroke rehabilitation. However, information about cost-
Clifton, E., Collins, M., Mead, G.E., van Wijck, F.   +3 more
core   +3 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source