Results 111 to 120 of about 4,521,628 (366)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Extended Cost-Effectiveness Analysis for Health Policy Assessment: A Tutorial
PharmacoEconomics (Auckland), 2016 Health policy instruments such as the public financing of health technologies (e.g., new drugs, vaccines) entail consequences in multiple domains. Fundamentally, public health policies aim at increasing the uptake of effective and efficient interventions
S. Verguet, Jane J. Kim, D. Jamison
semanticscholar +1 more source
Paying for cost-effective health care: Does it violate both static- and dynamic efficiency?
Nordic Journal of Health Economics, 2015 Recent research has questioned the rationales of using cost-effectiveness metrics of medical technologies to guide reimbursement. I discuss here the underlying ideas of this research, which argues that reimbursement based on cost effectiveness criteria ...
Tomas J Philipson
doaj +1 more source
Cost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. [PDF]
, 2000 Background Access to HIV-1 voluntary counseling and testing (VCT) is severely limited in less-developed countries. We undertook a multisite trial of HIV-1 VCT to assess its impact, cost, and cost-effectiveness in less-developed country settings.\ud ...
Balmer, D +7 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Cost-effectiveness of a potential Zika vaccine candidate: a case study for Colombia [PDF]
, 2018 Background: A number of Zika vaccine platforms are currently being investigated, some of which have entered clinical trials. We sought to evaluate the cost-effectiveness of a potential Zika vaccine candidate under the WHO Vaccine Target Product Profile ...
Moghadas, Seyed +2 more
core +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Cost-effectiveness Analysis of Schatzker V Tibial Plateau Fractures Treated with Locking Plate in a University Hospital [PDF]
, 2021 José Eduardo Nogueira Forni +3 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source