Results 51 to 60 of about 2,748,163 (380)

Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative

British medical journal, 2017
Objectives To evaluate the impact of total knee replacement on quality of life in people with knee osteoarthritis and to estimate associated differences in lifetime costs and quality adjusted life years (QALYs) according to use by level of symptoms ...
B. Ferket, Zach M. Feldman, Jing Zhou, E. Oei, S. Bierma-Zeinstra, M. Mazumdar   +5 more
semanticscholar   +1 more source

Convergence Analysis For Non Linear System Of Parabolic Variational Inequalities [PDF]

arXiv, 2021
This work aims to provide a comprehensive and unified numerical analysis for non linear system of parabolic variational inequalities (PVIs) subject to Dirichlet boundary condition. This analysis enables us to establish an existence of the exact solution to the considered model and to prove the convergence for the approximate solution and its ...
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Value of hospital resources for effective pressure injury prevention: a cost-effectiveness analysis

BMJ Quality & Safety, 2018
Objective Hospital-acquired pressure injuries are localised skin injuries that cause significant mortality and are costly. Nursing best practices prevent pressure injuries, including time-consuming, complex tasks that lack payment incentives.
W. Padula, P. Pronovost, M. Makic, H. Wald, D. Moran, Manish K. Mishra, D. Meltzer   +6 more
semanticscholar   +1 more source

Economic Evaluation of Health Interventions: A Critical Review

Iranian Journal of Public Health, 2022
Background: Economic evaluation is used for the optimal allocation of resources in the health sector. While a large number of economic evaluation studies have been conducted, there is less critical review of these studies.
Ali Mohammad Mosadeghrad, Ebrahim Jaafaripooyan, Mahmoud Zamandi   +2 more
doaj  

Decision Analysis and Cost-Effectiveness Analysis [PDF]

Seminars in Spine Surgery, 2009
Healthcare decision-making can be complex, often requiring decision makers to weigh serious trade-offs, consider patients' values, and incorporate evidence in the face of uncertainty. Medical decisions are made implicitly by clinicians and other decision-makers on a daily basis. Decisions based largely on personal experience are subject to many biases.
Jon D. Lurie, Anna N.A. Tosteson, Christene M. McDonough, Christene M. McDonough, Hilary F. Ryder   +4 more
openaire   +3 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis.

Health Technology Assessment, 2017
BACKGROUND Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk of thromboembolic events. Anticoagulation therapy to prevent AF-related stroke has been shown to be cost-effective.
N. Welton, A. McAleenan, H. Thom, P. Davies, W. Hollingworth, J. Higgins, G. Okoli, J. Sterne, G. Feder, D. Eaton, A. Hingorani, C. Fawsitt, T. Lobban, P. Bryden, A. Richards, R. Sofat   +15 more
semanticscholar   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Cost–Effectiveness Analysis in Pharmacogenomics [PDF]

Pharmacogenomics, 2010
The existence of finite healthcare budgets drives the need to consider opportunity cost and demonstrate that pharmacogenomic interventions offer added value, in terms of the relative costs and benefits, compared with current practice. This is where the framework of cost-effectiveness analysis is useful.
Katherine Payne, FH Shabaruddin
openaire   +3 more sources