Results 61 to 70 of about 26,692,564 (286)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cost-effectiveness analysis for trigeminal neuralgia: Cyberknife vs microvascular decompression

Neuropsychiatric Disease and Treatment, 2008
Rosanna Tarricone1, Giovanni Aguzzi1, Francesco Musi1, Laura Fariselli2, Andrea Casasco31Economic Evaluation Area, CERGAS Centre for Research on Healthcare Management-Bocconi University, Milan, Italy; 2Radiotherapy Department, Carlo Besta National ...
Rosanna Tarricone, Giovanni Aguzzi, Francesco Musi, Laura Fariselli, Andrea Casasco   +4 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cost-effectiveness analysis of intranasal live attenuated vaccine (LAIV) versus injectable inactivated influenza vaccine (TIV) for Canadian children and adolescents

ClinicoEconomics and Outcomes Research, 2012
Jean-Eric Tarride,1,2 Natasha Burke,1,2 Camilla Von Keyserlingk,1,2 Daria O'Reilly,1,2 Feng Xie,1,2 Ron Goeree1,21Programs for Assessment of Technology in Health (PATH) Research Institute, St Joseph's Healthcare Hamilton, Hamilton ...
Tarride JE, Burke N, Von Keyserlingk C, O'Reilly D, Xie F, Goeree R   +5 more
doaj  

Cost-effectiveness of linezolid to ventilator-associated pneumonia in Colombia

BMC Infectious Diseases
Introduction Ventilator-associated pneumonia (VAP) is a prominent cause of morbidity and mortality in intensive care unit (ICU) patients. Due to the increase in Methicillin resistant Staphylococcus aureus infection, it is important to consider other more
Jefferson Antonio Buendía, Diana Guerrero Patiño, Andrés Felipe Zuluaga Salazar   +2 more
doaj   +1 more source

Analysis of the Cost Effectivity in Treating Typhoid Fever in Children with Chloramphenicol and Ceftriaxone in Fatmawati Hospital Jakarta 2001 – 2002

Makara Journal of Health Research, 2010
This study was a cross-sectional study using secondary data related to treatment of typhoid fever in childhood. A total of 97 patients received chloramphenicol and 45 patients received ceftriaxone. The patients ranged in age from 1 to 15 years. Length of
Lili Musnelina, Ahmad Fuad Afdhal, Ascobat Gani, Pratiwi Andayani   +3 more
doaj   +1 more source

Thinking outside the box: recent advances in the analysis and presentation of uncertainty in cost-effectiveness studies [PDF]

, 2002
As many more clinical trials collect economic information within their study design, so health economics analysts are increasingly working with patient-level data on both costs and effects.
Briggs, Andrew H, Briggs, AH, O'Brien, B.J., Blackhouse, G, Briggs, A.H., O'Brien, Bernie J, Blackhouse, G., O'Brien, BJ, Brien, Bernie J, Blackhouse, Gordon   +9 more
core   +1 more source

Cost-effectiveness analysis results.

, 2022
Cost-effectiveness analysis results.
Mihaela Nica (3357893), Lorenzo Giovanni Mantovani (8674071), Paolo Angelo Cortesi (4175632), Claudio Gasperini (349160), Ippazio Cosimo Antonazzo (3177453), Daniela Ritrovato (6874883)   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Cost-effectiveness analysis of corticosteroid inhaler devices in primary care asthma management: A real world observational study

ClinicoEconomics and Outcomes Research, 2010
Linda Kemp1, John Haughney2, Neil Barnes3, Erika Sims1, Julie von Ziegenweidt1, Elizabeth V Hillyer1, Amanda J Lee4, Alison Chisholm1, David Price1,21Research in Real Life Ltd, Old Winery Business Park, Cawston, Norwich, UK; 2Centre of Academic Primary ...
Linda Kemp, John Haughney, Neil Barnes, et al   +3 more
doaj