Results 71 to 80 of about 1,659,263 (293)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

The Cost Analysis Using the Clinical Practice Guideline and Cost Minimization Analysis

Siriraj Medical Journal, 2008
Objective: The hospital revenues are decreasing from the government policy in the universal coverage while increasing the hospital expenses. The cost analysis is a very important tool for the strategic plan in the hospital expenses reduction with ...
Sureerat Thamrongsombatsakul
doaj  

A cost minimization analysis comparing minimally-invasive with open reduction surgical techniques for pelvic ring fracture

Experimental and Therapeutic Medicine, 2019
The aim of the present study was to compare the in-hospital direct medical costs of patients with pelvic fracture treated with minimally invasive surgery (MIS) or open reduction and internal fixation (ORIF).
Liang Ma, Lei Ma, Yu Chen, Yifeng Jiang, Qiang Su, Qian Wang, Yanhong Zhu   +6 more
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Cost analysis of technological vs. conventional upper limb rehabilitation for patients with neurological disorders: an Italian real-world data case study

Frontiers in Public Health
IntroductionMost patients suffering from neurological disorders endure varying degrees of upper limb dysfunction, limiting their everyday activities, with only a limited number regaining full arm use.
Valerio Gower, Irene Aprile, Francesca Falchini, Alessio Fasano, Marco Germanotta, Mattia Randazzo, Federico Spinelli, Leopoldo Trieste, Furio Gramatica, Giuseppe Turchetti   +9 more
doaj   +1 more source

Real-World Six-Year National Cost-Minimization Analysis of IncobotulinumtoxinA and OnabotulinumtoxinA in the VA/DoD Healthcare Systems

ClinicoEconomics and Outcomes Research, 2021
Rashid Kazerooni, 1 Ileana M Howard, 2, 3 Adrienne M Keener, 4, 5 Mark Bounthavong 6, 7 1Merz Pharmaceuticals, LLC, Raleigh, NC, 27615, USA; 2Rehabilitation Care Services, VA Puget Sound, Seattle, WA, USA; 3Department of Rehabilitation Medicine ...
Kazerooni R, Howard IM, Keener AM, Bounthavong M   +3 more
doaj  

Cost minimization analysis of line probe assay for detection of multidrug-resistant tuberculosis in Arkhangelsk region of Russian Federation

PLoS ONE, 2019
Background The development of new diagnostic tools allows for faster detection of both tuberculosis (TB) and multidrug-resistant (MDR) TB and should lead to reduced transmission by earlier initiation of anti TB therapy.
E. Bogdanova, A. Mariandyshev, G. Balantcev, P. Eliseev, Elena I Nikishova, A. Gaida, D. Enarson, A. Detjen, R. Dacombe, P. Phillips, S. Squire, E. Gospodarevskaya, E. Gospodarevskaya   +12 more
semanticscholar   +1 more source

Analysis of an information-theoretic model for communication

, 2012
We study the cost-minimization problem posed by Ferrer i Cancho and Sol\'e in their model of communication that aimed at explaining the origin of Zipf's law [PNAS 100, 788 (2003)]. Direct analysis shows that the minimum cost is $\min {\lambda, 1-\lambda}$
Altmann, Eduardo G., Dickman, Ronald, Moloney, Nicholas R.   +2 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Health economics and health preference concepts to orthopedics practitioners [PDF]

, 2014
The aim of this study was to describe concepts of health economics in order to update and provide the orthopedic practitioner decision making parameters based on preferences.
Abla, Luiz Eduardo Felipe, Araújo, Carlos Delano Mundim, Ferreira, Lydia Masako, Hochman, Bernardo, Novo, Neil Ferreira, Veiga, Daniela Francescato   +5 more
core   +1 more source