Results 71 to 80 of about 1,546,489 (336)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Cost Minimization Analysis of Same-Day Long-Acting Reversible Contraception for Adolescents [PDF]

, 2019
Importance: Long-acting reversible contraception (LARC) is considered first-line contraception for adolescents but often requires multiple clinic visits to obtain.
Downs, Stephen M., Tucker Edmonds, Brownsyne, Wilkinson, Tracey A.   +2 more
core   +1 more source

Estimating the economic life of forest machinery using the cumulative cost model and cost minimization model in Iranian Caspian forests

Journal of Forest Science, 2018
This study was conducted in order to estimate the economic life of two models of rubber-tired skidders, namely Timberjack 450C and HSM 904, in Iranian Caspian forests. The total annual costs and average cumulative cost of skidders were calculated by life-
Mohammad HEJAZIAN, Majid LOTFALIAN, Soleiman MOHAMMADI LIMAEI   +2 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Cost-minimization analysis of degludec/liraglutide versus glargine/aspart: economic implications of the DUAL VII study outcomes

ClinicoEconomics and Outcomes Research, 2018
Enrico Torre,1 Giacomo Matteo Bruno,2 Sergio Di Matteo,2 Chiara Martinotti,2 Martina Oselin,2 Maria Chiara Valentino,2 Alessio Parodi,3 Luigi Carlo Bottaro,4 Giorgio Lorenzo Colombo5 1Endocrinology, Diabetology and ...
Torre E, Bruno GM, Di Matteo S, Martinotti C, Oselin M, Valentino MC, Parodi A, Bottaro LC, Colombo GL   +8 more
doaj  

Cost savings with transcutaneous screening versus total serum bilirubin measurement for newborn jaundice in hospital and community settings: a cost-minimization analysis.

CMAJ Open, 2018
BACKGROUND Leading authorities in North America recommend universal screening via total serum bilirubin (TSB) measurement or transcutaneous bilirubinometry (TcB) for kernicterus prevention.
Stephanie McClean, K. Baerg, J. Smith-Fehr, M. Szafron   +3 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

The Cost Analysis Using the Clinical Practice Guideline and Cost Minimization Analysis

Siriraj Medical Journal, 2008
Objective: The hospital revenues are decreasing from the government policy in the universal coverage while increasing the hospital expenses. The cost analysis is a very important tool for the strategic plan in the hospital expenses reduction with ...
Sureerat Thamrongsombatsakul
doaj  

Comparative analyses of holder pasteurization vs. HTST pasteurization for donor milk: a cost-minimization study applicable to human milk banks

International Breastfeeding Journal, 2023
Background High-temperature short-time (HTST) pasteurization (72–75 °C, 15 s) is an alternative treatment to traditional Holder pasteurization (HoP) (62ºC, 30 min) for donor milk.
Diana Escuder Vieco, Jorge Arenas Vidal, Paula Rojas García, Marino J Gónzález, Nadia Raquel García Lara, Carmen Rosa Pallás Alonso   +5 more
doaj   +1 more source

Cost-minimization analysis in iron-deficiency anemia comparing intravenous ferric carboxymaltose to standard of care in pregnant women in Algeria

Journal of Applied Hematology, 2023
INTRODUCTION: Anemia due to iron deficiency is frequent during pregnancy and increases morbidity and mortality of mothers and infants. The objective of this study was to assess the economic consequences of intravenous ferric carboxymaltose (FCM) in ...
Lama Aladham, Nacera Benmouhoub, Mohamed Bradai, Amel Dammene-Debbih, Issam Frigaa, Karim Layaida, Lamine Mahi   +6 more
doaj   +1 more source