Results 31 to 40 of about 3,709,845 (162)

When Does SDG Adoption Increase ESG Risk? The Mediating Role of Risk Management

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Corporate engagement with the United Nations' Sustainable Development Goals (SDGs) has expanded rapidly, yet its implications for firms' environmental, social and governance (ESG) risk remain insufficiently understood. Prior research has focused on the performance outcomes of SDG adoption while largely overlooking its potential to generate ESG
Francisco J. López‐Arceiz   +1 more
wiley   +1 more source

Metrics to measure progress towards climate-smart agriculture (CSA) goals [PDF]

open access: yes, 2016
Climate-smart agriculture (CSA) aims to achieve the goals of increased productivity / food security, adaptation / resilience, and mitigation. The different weights put on each goal depends on the context.
CGIAR Research Program on Climate Change, Agriculture and Food Security
core   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

Cost-offset and sensitivity analyses (£).

open access: yes, 2013
Cost-offset and sensitivity analyses (£).
Stephen Butler (405083)   +4 more
core   +1 more source

A Parametric Computational Framework for Modeling and Seismic Design of Post‐Tensioned Mass Timber Rocking Walls

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Post‐tensioned cross‐laminated timber (PT‐CLT) rocking walls offer a compelling seismic system combining self‐centering behavior with energy dissipation. However, progress in their performance assessment and design has been limited by the lack of a comprehensive parametric modeling tool, as exists for steel or reinforced concrete systems. This
Ghasem B. Shargh   +3 more
wiley   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir   +4 more
wiley   +1 more source

Optimal‐Control 19F PROJECT Improves the Reliability of CPMG‐Derived Relaxation Rates

open access: yesMagnetic Resonance in Chemistry, EarlyView.
PROJECT with seedless optimal control pulses for 19F‐based protein‐ligand interaction screenings allows for a lower error in R2 estimates than those obtained with CPMG for J‐coupled fluorine signals and is indistinguishable from CPMG when the coupling is negligible, at the price of a modest reduction in SNR.
Marco Schiavina   +2 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Investigating the Environmental Impact of Additive Construction: A Systematic Analysis of the Life Cycle Assessment Studies

open access: yesSustainable Development, EarlyView.
ABSTRACT Additive Manufacturing (AM) has been identified as a potential catalyst for a paradigm shift within the construction industry, due to its capacity to enhance sustainability, reduce waste, and augment design flexibility. This study presents a systematic literature review (SLR) that explores the application of Life Cycle Assessment (LCA) in ...
Antonio Mastropasqua   +3 more
wiley   +1 more source

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