Results 41 to 50 of about 1,078,518 (304)
METHODS OF ANALYSIS OF THE EFFECTIVENESS OF PUBLIC SECTOR PROJECTS: FEATURES AND CONSTRAINTS [PDF]
The purpose of the paper is to consider the main provisions of methods of analysis of the effectiveness of public sector projects. A number of issues remain controversial in the methodology of analysing costs and benefits.
Volodymyr Lipkan +2 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Cost utility of fractional exhaled nitric oxide monitoring for the management of children asthma [PDF]
Introduction Fractional exhaled nitric oxide is a simple, non-invasive measurement of airway inflammation with minimal discomfort to the patient and with results available within a few minutes.
Acuña-Cordero, Ranniery +2 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Comparison of EQ-5D-3L with QLU-C10D in Metastatic Melanoma Using Cost-Utility Analysis
BackgroundThe National Institute for Health and Care Excellence (NICE) prefers the use of the generic EQ-5D instrument to estimate quality-adjusted life years (QALYs), and recommends that condition-specific instruments only be used when EQ-5D data are ...
Kim, H +7 more
core +1 more source
A new outcome measure for cost-utility analyses of screening programs [PDF]
We show that, under some plausible assumptions, the gain in QALYs a screening program offers is a positive linear transformation of the program's sensitivity level.
Juan D. Moreno-Ternero, Carmen Herrero
core +2 more sources
Cost-utility analysis of nonalcoholic steatohepatitis screening [PDF]
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in Western countries. No studies have examined the cost-effectiveness of screening its advanced form, nonalcoholic steatohepatitis (NASH).We performed a cost-utility analysis of annual noninvasive screening strategies using third-party payer perspective in a general population in
Eric, Zhang +5 more
openaire +2 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Standardizing cost-utility analysis in neurosurgery
This review seeks to introduce the concept of cost-utility analysis in neurosurgery and to highlight its essential components. It also includes a suggested approach to standardization, which would help bring more credence to this research and potentially affect management choices, reimbursement, and policy.
Jared D, Ament, Kee D, Kim
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

