Results 31 to 40 of about 1,296,802 (307)

Fair Transmission Expansion Cost Allocation for Renewable Energy Resource Interconnection Based on Stochastic Cooperative Game Theory

Mathematics
We propose a fair transmission expansion cost allocation (CA) algorithm and a fair process to build alternative transmission expansion plans. We define fairness such that each participant’s payment does not exceed its own benefit and the total payment ...
Youngjun Go, Wonseok Choi, Minsung Kim, Jin-Ho Chung, Hyeonjin Kim, Duehee Lee   +5 more
doaj   +1 more source

Resource Competition on Integral Polymatroids [PDF]

, 2014
We study competitive resource allocation problems in which players distribute their demands integrally on a set of resources subject to player-specific submodular capacity constraints.
A. Haurie, D. Fotakis, E. Anshelevich, F. Kelly, H. Ackermann, H. Chen, H.L. Chen, I. Milchtaich, I. Milchtaich, J. Dunkel, L. Tran-Thanh, M. Beckmann, M. Gairing, P. Falkenhausen von, P. Krysta, R. Johari, R. Rosenthal, R. Rosenthal, R. Srikant, S. Antonakopoulos, T. Harks, T. Roughgarden, U. Faigle   +22 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Financial Opportunities and Challenges in Energy Communities: Revenue, Costs, and Capital Structures

Energies
Energy Communities (ECs) have emerged as central legal instruments for decentralized renewable energy deployment across Europe; however, their long-term viability depends critically on financial sustainability mechanisms that remain inadequately ...
Saeed Khorrami, Maria Carmen Falvo, Massimo Pompili   +2 more
doaj   +1 more source

Cost monotonicity, consistency and minimum cost spanning tree games [PDF]

, 2002
We propose a new cost allocation rule for minimum cost spanning tree games. The new rule is a core selection and also satisfies cost monotonicity. We also give characterization theorems for the new rule as well as the much-studied Bird allocation.
Dutta, Bhaskar, Kar, Anirban
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cost-effectiveness analysis of adding durvalumab to chemotherapy as first-line treatment for advanced biliary tract cancer based on the TOPAZ-1 trial

Cost Effectiveness and Resource Allocation, 2023
Background Durvalumab plus gemcitabine and cisplatin has a significant clinical benefit for advanced biliary tract cancer (BTC). However, the high price of durvalumab warrants an exploration of the economics.
Qiuling Zhao, Ruixiang Xie, Wanfu Zhong, Wenbin Liu, Ting Chen, Xiuliang Qiu, Lin Yang   +6 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Essential emergency and critical care as a health system response to critical illness and the COVID19 pandemic: what does it cost?

Cost Effectiveness and Resource Allocation, 2023
Essential Emergency and Critical Care (EECC) is a novel approach to the care of critically ill patients, focusing on first-tier, effective, low-cost, life-saving care and designed to be feasible even in low-resourced and low-staffed settings.
Lorna Guinness, Angela Kairu, August Kuwawenaruwa, Karima Khalid, Khamis Awadh, Vincent Were, Edwine Barasa, Hiral Shah, Peter Baker, Carl Otto Schell, Tim Baker   +10 more
doaj   +1 more source

Water Allocation Mechanisms: Principles and Examples [PDF]

, 1997
From the earliest times, water resources have been allocated on the basis of social criteria - maintaining the community by ensuring that water is available for human consumption, for sanitation, and for food production.
Ariel Dinar, Mark W. Rosegrant, Ruth Suseela Meinzen-Dick   +2 more
core   +1 more source