Results 31 to 40 of about 7,336,661 (310)

The evolution of Earth Observation: exploring space sustainability through European case studies

open access: yesInternational Journal of Sustainable Engineering
In September 2015, the United Nations launched the 2030 Agenda for Sustainable Development, followed by the adoption of the ‘Space2030’ Agenda in October 2021, highlighting the importance of space and Earth Observation (EO) data in monitoring progress ...
Elisabetta Lamboglia   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Realtime market microstructure analysis: online Transaction Cost Analysis [PDF]

open access: yes, 2013
Motivated by the practical challenge in monitoring the performance of a large number of algorithmic trading orders, this paper provides a methodology that leads to automatic discovery of the causes that lie behind a poor trading performance.
Azencott, Robert   +5 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cost-benefit analysis and valuation uncertainty [PDF]

open access: yes, 2007
This thesis addresses the economic trade-offs between hydropower and fish production, based on an empirical assessment of the costs and benefits of changing the water flow of the Ume/Vindel River in northern Sweden at a major hydropower plant in ways ...
Håkansson, Cecilia
core  

Brain network analysis : separating cost from topology using cost-integration [PDF]

open access: yes, 2011
A statistically principled way of conducting brain network analysis is still lacking. Comparison of different populations of brain networks is hard because topology is inherently dependent on wiring cost, where cost is defined as the number of edges in
Ginestet, Cedric E.   +3 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Cost-Benefit Analysis of Reclaiming Futures [PDF]

open access: yes, 2010
Assesses the costs of RWJF's initiative to improve substance abuse interventions for youth with improved service delivery, cooperation, and family involvement; estimates behavior change and reduction in juvenile crime; and considers returns on ...

core  

Delivering diabetes education through nurseled telecoaching : cost-effectiveness analysis [PDF]

open access: yes, 2016
Background : People with diabetes have a high risk of developing micro-and macrovascular complications associated with diminished life expectancy and elevated treatment costs. Patient education programs can improve diabetes control in the short term, but
Aertgeerts, Bert   +5 more
core   +3 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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