Results 61 to 70 of about 26,464,921 (304)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Administration of intravenous morphine for acute pain in the emergency department inflicts an economic burden in Europe

Drugs in Context, 2018
Background: Acute pain is among the leading causes of referral to the emergency department (ED) in industrialized countries. Its management mainly depends on intensity.
Montserrat Casamayor, Karen DiDonato, Marc Hennebert, Luca Brazzi, Gregor Prosen   +4 more
doaj   +1 more source

Cost-Consequence Analysis of Mobile Stroke Units vs. Standard Prehospital Care and Transport

Frontiers in Neurology, 2020
Background: Mobile stroke units (MSUs) are the latest approach to improving time-sensitive stroke care delivery. Currently, there are no published studies looking at the expanded value of the MSU to diagnose and transport patients to the closest most ...
Andrew P. Reimer, Andrew P. Reimer, Atif Zafar, Fredric M. Hustey, Damon Kralovic, Andrew N. Russman, Ken Uchino, Muhammad S. Hussain, Belinda L. Udeh, Belinda L. Udeh   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Battery Control for Node Capacity Increase for Electric Vehicle Charging Support

Energies
The integration of electric vehicles (EVs) into the power grid poses significant challenges and opportunities for energy management systems. This is especially concerning for parking lots or private building condominiums in which refurbishing is not ...
Md Wakil Ahmad, Alexandre Lucas, Salvador Moreira Paes Carvalhosa   +2 more
doaj   +1 more source

Efficiency and costs of different concentrated solar power plant configurations for sites in Gauteng and the Northern Cape, South Africa

Journal of Energy in Southern Africa, 2017
Concentrated solar power (CSP) plants can play a major role in the future South African electricity mix. Today the Independent Power Producer (IPP) Procurement Programme aims to facilitate renewable energy projects to access the South African energy ...
Thomas Telsnig, Ludger Eltrop, Hartmut Winkler, Ulrich Fahl   +3 more
doaj   +1 more source

Cost-effectiveness analysis.

, 2023
Managing tibial fractures requires substantial health resources, which costs the health system. This study aimed to describe the costs of photobiomodulation (PBM) with LEDs in the healing process of soft tissue lesions associated with tibial fracture ...
Lara Jansiski Motta (8681628), Raquel Agnelli Mesquita-Ferrari (8681631), Kristianne Porta Santos Fernandes (8681625), Sandra Kalil Bussadori (8621904), Estela Capelas Barbosa (12248581), Frederico Carlos Jana Neto (17605045), Ana Luiza Cabrera Martimbianco (5454077), Fernanda Carolina Felix (17605051), Cinthya Cosme Gutierrez Duran (17605054), Diogo Valvano de Medeiros (17605048)   +9 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Comparative Assessment of Fractional and Erosion Plot Methods for Quantifying Soil Erosion and Nutrient Loss Under Vetiver Grass Technology on Two Contrasting Slopes in Rainforest Agroecology

Agriculture
The erosion plot method (EPM) is the most accurate method for measuring total runoff and soil loss in the field, but it is expensive, time-consuming, and tedious to use, thereby limiting the scope of soil erosion research.
Suarau O. Oshunsanya, Hanqing Yu, Ayodeji M. Odebode, Ini D. Edem, Tunde S. Oluwatuyi, Esther E. Imasuen, Dorcas E. Odeyinka   +6 more
doaj   +1 more source

The direct medical costs of colorectal cancer in Iran; analyzing the patient′s level data from a cancer specific hospital in Isfahan

International Journal of Preventive Medicine, 2012
Background: The Immense cost of cancer treatment is one of the main challenges of health care systems all over the world including Iran. The aim of this study was to analyze the direct treatment costs of colorectal cancer patients in Isfahan, Iran ...
Majid Davari, Mohammad R Maracy, Mohamad H Emami, Diana Taheri, Abolfazl Aslani, Mahshid Givi, Saeid Massah   +6 more
doaj   +1 more source