Results 71 to 80 of about 7,336,661 (310)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Cost-Benefit Analysis of a Redundant System with Server having Refreshment Facility Subject to Inspection [PDF]
, 2017 In this paper two units cold standby system has been discussed with the facility that server inspect the failed unit before repair/replacement of the unit and server may allow to take refreshment whenever needed. The operative unit may fail directly from
Barak, M. S. (M) +2 more
core +1 more source
Economic aspects of airspace control and protection [PDF]
Megatrend Revija, 2018 Airspace control and protection is extremely significant task for every state from security, political, economic and other points of view. However, airspace control requires engagement of technology and people.
Kankaraš Milan +3 more
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
VaccinesThis review evaluates the financial burden of current treatments for triple-negative breast cancer (TNBC) and projects potential financial scenarios to assess the feasibility of introducing a peptide-based neoantigen cancer vaccine (NCV) targeting the ...
Adriana Novakova +3 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Radar altimetry systems cost analysis [PDF]
This report discusses the application and cost of two types of altimeter systems (spaceborne (satellite and shuttle) and airborne) to twelve user requirements.
Denman, W. F., Escoe, D., Heuring, F. T.
core +1 more source
Submit an analysis of cost savings attributed to Challenge activities implemented at your school [PDF]
, 2016 Assessing the economic impact of any changes in procedure and documenting any cost savings can help make the case for cost competitiveness of food waste reduction and prevention efforts.
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