Results 41 to 50 of about 1,436,686 (263)

Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism

open access: yesFrontiers in Energy Research
With the continuous maturation of the sharing economy model, the shared energy storage station service model emerges as a promising user-side energy storage application.
Hongde Ma, Weiqi Zhang, Ziqing Luo
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Developing a cost-payment coordination model for project cost flow forecasting / Sąnaudų ir mokėjimo koordinavimo modelio, skirto projektų sąnaudų srautų prognozėms, kūrimas

open access: yesJournal of Civil Engineering and Management, 2011
Project operating cash flow forecasting techniques have evolved to enable detailed predictions relating to individual projects. These techniques, principally the cost-schedule integration (CSI) model, extensively use project cost estimates and schedule ...
Hong Long Chen   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Optimización de los costos de muestreo en la manufactura de shampoo y acondicionador

open access: yesIngeniería Industrial, 2018
Optimizar los costos en el proceso de muestreo en la producción de shampoo y acondicionador a través del diseño bibliográfico, debido a trabajos previos de investigación en temas de producción, muestreo y calidad en diferentes ramas industriales entre ...
María del Carmen Rosas-Guerrero   +1 more
doaj   +1 more source

Application of BIM technology in construction management of gas station

open access: yesYou-qi chuyun, 2020
As the gas station is an important part of urban natural gas transmission and distribution system, the level of its construction management has a very significant impact on construction quality, project schedule, investment benefit and safe operation of ...
Yonghua WANG   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy