Results 61 to 70 of about 26,659,160 (338)
Path integral formulation of stochastic optimal control with generalized costs
, 2014 Path integral control solves a class of stochastic optimal control problems with a Monte Carlo (MC) method for an associated Hamilton-Jacobi-Bellman (HJB) equation.
Chorin, Alexandre J. +3 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Journal of Civil Engineering and Management, 2011 Project operating cash flow forecasting techniques have evolved to enable detailed predictions relating to individual projects. These techniques, principally the cost-schedule integration (CSI) model, extensively use project cost estimates and schedule ...
Hong Long Chen +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
On the cost of null-control of an artificial advection-diffusion problem
, 2013 In this paper we study the null-controllability of an artificial advection-diffusion system in dimension $n$. Using a spectral method, we prove that the control cost goes to zero exponentially when the viscosity vanishes and the control time is large ...
Cornilleau, Pierre, Guerrero, Sergio
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Prevention and Cost Control [PDF]
Science, 2012 Prevention is the key to cost control and improving the quality of health care in many nations. Most people think of prevention as vaccines and screening tests. But it is tertiary prevention—keeping people with established diseases from becoming worse—that holds the greatest promise for strengthening the health care system. Why?
openaire +2 more sources
Optimal controller/observer gains of discounted-cost LQG systems
, 2018 The linear-quadratic-Gaussian (LQG) control paradigm is well-known in literature. The strategy of minimizing the cost function is available, both for the case where the state is known and where it is estimated through an observer.
Bijl, Hildo, Schön, Thomas B.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Optimización de los costos de muestreo en la manufactura de shampoo y acondicionador
Ingeniería Industrial, 2018 Optimizar los costos en el proceso de muestreo en la producción de shampoo y acondicionador a través del diseño bibliográfico, debido a trabajos previos de investigación en temas de producción, muestreo y calidad en diferentes ramas industriales entre ...
María del Carmen Rosas-Guerrero +1 more
doaj +1 more source