Results 61 to 70 of about 14,195,110 (309)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Costing the distribution of insecticide-treated nets: a review of cost and cost-effectiveness studies to provide guidance on standardization of costing methodology. [PDF]
, 2006 BACKGROUND: Insecticide-treated nets (ITNs) are an effective and cost-effective means of malaria control. Scaling-up coverage of ITNs is challenging. It requires substantial resources and there are a number of strategies to choose from.
Kolaczinski, Jan +7 more
core +1 more source
Optimización de los costos de muestreo en la manufactura de shampoo y acondicionador
Ingeniería Industrial, 2018 Optimizar los costos en el proceso de muestreo en la producción de shampoo y acondicionador a través del diseño bibliográfico, debido a trabajos previos de investigación en temas de producción, muestreo y calidad en diferentes ramas industriales entre ...
María del Carmen Rosas-Guerrero +1 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2018 A) Cost-effectiveness plan of pharmaceutical care for years; B) Cost-effectiveness plan of pharmaceutical care for period. By period the mean cost and pressure control percentage of their years was used to compare periods of pharmaceutical care and post ...
Maurílio de Souza Cazarim (2838158) +1 more
core +1 more source
Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda. [PDF]
, 2011 BACKGROUND: Current Uganda National Malaria treatment guidelines recommend parasitological confirmation either by microscopy or rapid diagnostic test (RDT) before treatment with artemether-lumefantrine (AL).
Nuwaha, Fred +12 more
core +1 more source
Application of BIM technology in construction management of gas station
You-qi chuyun, 2020 As the gas station is an important part of urban natural gas transmission and distribution system, the level of its construction management has a very significant impact on construction quality, project schedule, investment benefit and safe operation of ...
Yonghua WANG +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Configurations of Control: A Transaction Cost Approach [PDF]
In this paper, I present a theory of management control based on Transaction Cost Economics.This theory seeks to integrate into a single framework a set of insights as to the natureof the organization's activities, the control problems that are inherent ...
Spekle, R.F.
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source