Results 71 to 80 of about 13,619,579 (305)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Effectiveness of the actions of antimicrobial's control in the intensive care unit

open access: yesBrazilian Journal of Infectious Diseases, 2003
There are various strategies to improve the effectiveness of antibiotics in hospitals. In general, the implementation of guidelines for appropriate antibiotic therapy and the participation of infectious disease (ID) physicians deserve considerable ...
Santos Edilson Floriano dos   +3 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Passive and active control systems for adaptive glazing facades and envelopes

open access: yes, 2015
This book is based upon work from COST Action TU 1403 adaptive facade network, supported by COST (European Cooperation in Science and Technology). COST (European Cooperation in Science and Technology) is a pan-European intergovernmental framework.
AMADIO, CLAUDIO   +3 more
core  

Cost-Sensitive Learning for Confidential Access Control

open access: yes, 2018
It is common to control access to critical information based on the need-to-know principle; The requests for access are authorized only if the content of the requested information is relevant to the requester’s project. We formulate such a dichotomous
Young Woo Seo (5400101)   +2 more
core   +1 more source

Research on Cost Control of Railway Engineering Based on Grounded Theory

open access: yesBuildings
An analysis of cost management within railway construction projects has been conducted using the Analytic Hierarchy Process (AHP) and a regression analysis to evaluate and rank key financial and operational factors affecting project costs.
Di Meng, Zhiqi Sun
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Yaw control of helicopter: an adaptive guaranteed cost control approach

open access: yes, 2009
This paper discusses the adaptive robust guaranteed cost tracking control problem of linear systems with time-varying uncertainties. The bounds of varying uncertainty ellipsoidal are obtained by set membership identification method. The proposed adaptive
Zhao XG(赵新刚), Han JD(韩建达)
core  

Optimal periodic output feedback control: a continuous-time approach [PDF]

open access: yes, 2007
: This paper addresses the problem of optimal static output feedback control of linear periodic systems. The proposed approach, which allows to deal with both stable and unstable open loop systems, relies on a continuous-time formulation of the control ...
VIGANO', LUCA   +8 more
core   +1 more source

The steering and control of central government Non-Departmental Public Bodies in Italy

open access: yes, 2008
Governments in many countries have established semi-autonomous single-purpose organisations (OECD, 2002); ministries and other departmental bodies have been split up into several entities and these entities, disaggregated from a leaner core government ...
FEDELE, Paolo   +3 more
core   +1 more source

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