Results 81 to 90 of about 26,659,160 (338)

Effectiveness of the actions of antimicrobial's control in the intensive care unit

open access: yesBrazilian Journal of Infectious Diseases, 2003
There are various strategies to improve the effectiveness of antibiotics in hospitals. In general, the implementation of guidelines for appropriate antibiotic therapy and the participation of infectious disease (ID) physicians deserve considerable ...
Santos Edilson Floriano dos   +3 more
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Systematic preoperative approach for bariatric surgery, perioperative results, and economic impact

open access: yesFrontiers in Public Health
IntroductionObesity is a complex systemic condition, involving numerous anatomical and metabolic changes. Therefore, a comprehensive preoperative assessment is essential for each patient contemplating bariatric surgery.ObjetiveThis study presents the ...
Iolanda Freire-Moreira   +13 more
doaj   +1 more source

Controlling the cost of risk management by utilising a phase portrait methodology

open access: yesTransport, 2018
The methodology developed in this study presents an approach to the concurrent evaluation of Risk Management (RM) effectiveness during project execution.
David Eaton   +2 more
doaj   +1 more source

Linear Quadratic Games with Costly Measurements

open access: yes, 2017
In this work we consider a stochastic linear quadratic two-player game. The state measurements are observed through a switched noiseless communication link. Each player incurs a finite cost every time the link is established to get measurements.
Anastasopoulos, Achilleas   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

AN ECONOMIC EFFICIENCY IN VOJVODINA DAIRY PRODUCTION

open access: yesEkonomika Poljoprivrede (1979), 2006
In examining economic performance of dairy sector, technical and economic efficiency are the most frequently applied concepts. This research is based on data for 20 dairy farms across Province of Vojvodina in 2003.
Rade Popovic
doaj  

A BIM-Based Integrated Model for Low-Cost Housing Mass Customization in Brazil: Real-Time Variability with Data Control

open access: yesArchitecture
Addressing the growing demand for affordable housing requires innovative solutions that strike a balance between cost efficiency and user-specific needs.
Alexander Lopes de Aquino Brasil   +1 more
doaj   +1 more source

A coordination mechanism with fair cost allocation for divergent multi-echelon inventory systems [PDF]

open access: yes, 2009
This paper is concerned with the coordination of inventory control in divergent multiechelon inventory systems under periodic review and decentralized control. All the installations track echelon inventories. Under decentralized control the installations
Timmer, Judith
core   +2 more sources

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